Evidence map›Paper›PMID 28031710›Full record

ArticleInternational journal of nanomedicine

A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization.

Navya Sree Kola Srinivas, Ruchi Verma, Girish Pai Kulyadi, Lalit Kumar

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  10. Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Navya Sree Kola SrinivasDepartment of Pharmaceutics.
Ruchi VermaDepartment of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India.
Girish Pai KulyadiDepartment of Pharmaceutics.
Lalit KumarDepartment of Pharmaceutics.
American Pharmacists Association · USManipal Academy of Higher Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gefitinib is an anticancer agent which acts by inhibiting epidermal growth factor receptor tyrosine kinase receptors. The aim of the present study was to prepare gefitinib nanosuspension. Gefitinib was encapsulated in Eudragit

Indexed as

NanoparticlesAnimalsBiological AvailabilityChlorocebus aethiopsDrug CarriersFemaleGefitinibHalf-LifeParticle SizePolymethacrylic AcidsPolyvinyl AlcoholPovidoneQuinazolinesRats, WistarSuspensionsVero CellsDrug CarriersGefitinibmethylmethacrylate-methacrylic acid copolymerPolymethacrylic AcidsPolyvinyl AlcoholPovidoneQuinazolinesSuspensionsbioavailabilityBiopharmaceutical Classification System class IIcancerdesign of experimentepidermal growth factor receptor tyrosine kinase receptors inhibitorEudragit® RL100full factorial designgefitinibPVAPVP K30QbD

Identifiers

PMID28031710
PMCPMC5179202
OpenAlexW2563565179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.