Evidence map›Paper›PMID 28031481›Full record

ArticleRNA (New York, N.Y.)2017

James A Toombs, Yuliya A Sytnikova, Gung-Wei Chirn, Ignatius Ang, Nelson C Lau, Michael D Blower

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. PIWI proteins and piRNAs: key regulators of stem cell biology.Frontiers in cell and developmental biology · 2025
    Review
  2. Insights in piRNA targeting rules.Wiley interdisciplinary reviews. RNA · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

James A ToombsDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Yuliya A SytnikovaDepartment of Biology and Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, Massachusetts 02454, USA.
Gung-Wei ChirnDepartment of Biology and Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, Massachusetts 02454, USA.
Ignatius AngDepartment of Biology and Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, Massachusetts 02454, USA.
Nelson C LauDepartment of Biology and Rosenstiel Basic Medical Science Research Center, Brandeis University, Waltham, Massachusetts 02454, USA.ORCID 0000-0001-9907-1404
Michael D BlowerDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID 0000-0002-5037-1972
Brandeis University · USHarvard University · US

Funding

Mouse CoreP30NS045713 · NINDS · BRANDEIS UNIVERSITY · PI ROSBASH, MICHAEL · 2003 to 2013
$7.8M
Transposon landscapes and transcriptome diversity in aging neuronsR01AG052465 · NIA · BRANDEIS UNIVERSITY · PI LAU, NELSON C · 2016 to 2020
$2.0M
Genome-wide analysis of polyadenylation and translation in XenopusR01GM108548 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BLOWER, MICHAEL DEMIAN · 2014 to 2017
$1.7M
Analysis of microtubule localized RNAsR01GM086434 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BLOWER, MICHAEL DEMIAN · 2009 to 2013
$1.6M
The Function of piRNAs and the piRNA ComplexR00HD057298 · NICHD · BRANDEIS UNIVERSITY · PI LAU, NELSON C · 2009 to 2011
$706k
THE IMPACT OF PIWI ASSOCIATED TRANSCRIPTS IN XENOPUS GERM CELL DEVELOPMENTR21HD088792 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAU, NELSON C · 2017 to 2018
$469k
NIA NIH HHS R01 AG052465NICHD NIH HHS R00 HD057298NICHD NIH HHS R21 HD088792NIGMS NIH HHS R01 GM086434NIGMS NIH HHS R01 GM108548NINDS NIH HHS P30 NS045713
6 · The paper itself

Abstract

Piwi proteins utilize small RNAs (piRNAs) to recognize target transcripts such as transposable elements (TE). However, extensive piRNA sequence diversity also suggests that Piwi/piRNA complexes interact with many transcripts beyond TEs. To determine Piwi target RNAs, we used ribonucleoprotein-immunoprecipitation (RIP) and cross-linking and immunoprecipitation (CLIP) to identify thousands of transcripts associated with the Piwi proteins XIWI and XILI (Piwi-protein-associated transcripts, PATs) from early stage oocytes of

Indexed as

Gene Expression Regulation, DevelopmentalTranscriptomeAnimalsArgonaute ProteinsBiological AssayDNA Transposable ElementsDrosophila ProteinsEmbryonic DevelopmentFemaleOocytesOogenesisPhylogenyProtein BindingRNA, MessengerRNA, Small InterferingXenopusArgonaute ProteinsDNA Transposable ElementsDrosophila Proteinspiwi protein, DrosophilaRNA, MessengerRNA, Small InterferingXenopus ProteinsoocytePiwiXenopusXILIXIWI

Identifiers

PMID28031481
PMCPMC5340914
OpenAlexW2563373732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.