Evidence map›Paper›PMID 28031460›Full record

ArticleThe Journal of biological chemistry2017

The Inhibitory Role of α2,6-Sialylation in Adipogenesis.

Tomoko Kaburagi, Yasuhiko Kizuka, Shinobu Kitazume, Naoyuki Taniguchi

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. ST6Gal1: Oncogenic signaling pathways and targets.Frontiers in molecular biosciences · 2022
    Review
  7. Review
  8. Targeting Epigenetic Mechanisms in Vascular Aging.Frontiers in cardiovascular medicine · 2021
    Review
  9. Protein Glycosylation in Diabetes.Advances in experimental medicine and biology · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Restricted processing of CD16a/Fc γ receptor IIIaThe Journal of biological chemistry · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Tomoko KaburagiFrom the Department of Health Science, Faculty of Sports and Health Sciences, Daito Bunka University, Higashi-Matsuyama, Saitama 355-8681, Japan and t-kabu@ic.daito.ac.jp.
Yasuhiko Kizukathe Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Global Research Cluster, RIKEN, Wako, Saitama 351-0198, Japan.ORCID 0000-0002-3181-9743
Shinobu Kitazumethe Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Global Research Cluster, RIKEN, Wako, Saitama 351-0198, Japan.ORCID 0000-0003-4757-723X
Naoyuki Taniguchithe Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Global Research Cluster, RIKEN, Wako, Saitama 351-0198, Japan dglycotani@riken.jp.
RIKEN · JPDaito Bunka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue plays critical roles in obesity and related diseases such as diabetes and cardiovascular diseases. Previous reports suggest that glycans, the most common posttranslational modifications, are involved in obesity-related diseases, but what type of glycan regulates adipogenesis during obesity remains unclear. In this study, we first quantified the mRNA levels of 167 genes (encoding 144 glycosyltransferases and 23 related enzymes) in visceral adipose tissues (VATs) from control mice and high-fat diet (HFD)-induced obese mice. We found that a gene encoding β-galactoside α2,6-sialyltransferase-1 (

Indexed as

Adipogenesis3T3-L1 CellsAnimalsbeta-D-Galactoside alpha 2-6-SialyltransferaseDiet, High-FatDown-RegulationIntegrin beta1Intra-Abdominal FatMaleMiceMice, Inbred C57BLMice, KnockoutObesitySialyltransferasesSignal Transductionbeta-D-Galactoside alpha 2-6-SialyltransferaseIntegrin beta1Sialyltransferasesadipose tissueDNA methylationglycosylationglycosyltransferaseintegrin-β1obesityβ-galactoside α-2,6-sialyltransferase 1 (ST6GAL1)

Identifiers

PMID28031460
PMCPMC5313100
OpenAlexW2560928331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.