Evidence map›Paper›PMID 28031436›Full record

ArticleJournal of clinical microbiology2017

Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages.

M D Cairns, M D Preston, C L Hall, D N Gerding, P M Hawkey, H Kato, H Kim, E J Kuijper, T D Lawley, H Pituch and 8 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Pathogens (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Microbial genomics · 2025
    Article
  5. Distribution ofEmerging microbes & infections · 2024
    Article
  6. Clinical microbiology reviews · 2024
    Review
  7. Comparative Genomics of Clostridioides difficile.Advances in experimental medicine and biology · 2024
    Article
  8. Genomic and phenotypic characterization of aFrontiers in cellular and infection microbiology · 2024
    Article
  9. Antibiotic Resistances of Clostridioides difficile.Advances in experimental medicine and biology · 2024
    Article
  10. Article
  11. Systems biology approach to functionally assess theProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Genomic evolution and virulence association ofEmerging microbes & infections · 2021
    Article
  14. Mechanisms of antibiotic resistance of Clostridioides difficile.The Journal of antimicrobial chemotherapy · 2021
    Review
  15. Article
  16. Article
  17. Comparative genomics ofMicrobial genomics · 2020
    Article
  18. A publicly accessible database forMicrobial genomics · 2020
    Article
  19. The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Observational
  20. Emerging microbes & infections · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

M D CairnsDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
M D PrestonNational Institute for Biological Standards and Control, South Mimms, United Kingdom.
C L HallDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
D N GerdingEdward Hines, Jr., Veterans Affairs Hospital, Hines, Illinois, USA.
P M HawkeyInstitute of Microbiology and Infection, University of Birmingham, Edgbaston Campus, Birmingham, United Kingdom.
H KatoDepartment of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan.
H KimDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea.
E J KuijperNational Reference Laboratory for Clostridium difficile, Leiden University Medical Centre and RIVM, Bilthoven, The Netherlands.
T D LawleyWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom.
H PituchDepartment of Medical Microbiology, Medical University of Warsaw, Warsaw, Poland.
S ReidDepartment of Molecular and Cell Biology, University of Cape Town, Rondebosch, South Africa.
B KullinDepartment of Molecular and Cell Biology, University of Cape Town, Rondebosch, South Africa.
T V RileyThe University of Western Australia, School of Pathology and Laboratory Medicine, Crawley, Australia.
K SolomonSchool of Medicine and Medical Science, UCD Veterinary Sciences Centre, University College Dublin, Belfield, Dublin, Ireland.
P J TsaiDepartment of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Medical College, Tainan, Taiwan.
J S WeeseDepartment of Pathobiology, University of Guelph, Guelph, Ontario, Canada.
R A StablerDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID 0000-0002-2402-6630
B W WrenDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom Brendan.Wren@lshtm.ac.uk.

Funding

Medical Research Council G1000214Medical Research Council MR/K000551/1Wellcome Trust
6 · The paper itself

Abstract

The diarrheal pathogen

Indexed as

Genetic VariationPhylogenyRibotypingAnimalsClostridioides difficileClostridium InfectionsGenome, BacterialGlobal HealthHumansMolecular EpidemiologyPolymerase Chain ReactionSequence Analysis, DNAantibiotic resistanceClostridium difficileevolutionphylogeneticsphylogenyribotype 017sequencingSNPs

Identifiers

PMID28031436
PMCPMC5328454

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.