Evidence map›Paper›PMID 28031432›Full record

ReviewJournal of clinical microbiology2017

Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship.

Kevin Messacar, Sarah K Parker, James K Todd, Samuel R Dominguez

Abstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Evaluation of the NG-TESTJAC-antimicrobial resistance · 2026
    Article
  9. Article
  10. Article
  11. SiOMikrochimica acta · 2026
    Article
  12. ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  13. Deciphering the Implications ofPathogens (Basel, Switzerland) · 2026
    Review
  14. Challenges and opportunities in the management of severe pneumonia. Key concepts from the Seventh Annual Meeting of Spanish Experts 2025.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Clinical adjudication approach for rapid diagnostics aiming to identify bacteria directly from blood.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2026
    Article
  20. Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kevin MessacarSection of Hospital Medicine, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA kevin.messacar@childrenscolorado.org.
Sarah K ParkerSection of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
James K ToddSection of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
Samuel R DominguezSection of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.

Funding

Implementation and Effectiveness of a Rapid Cerebrospinal Fluid Diagnostics Program for Children with Suspected Central Nervous System InfectionK23AI128069 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MESSACAR, KEVIN BRETT · 2017 to 2021
$878k
NIAID NIH HHS K23 AI128069
6 · The paper itself

Abstract

New rapid molecular diagnostic technologies for infectious diseases enable expedited accurate microbiological diagnoses. However, diagnostic stewardship and antimicrobial stewardship are necessary to ensure that these technologies conserve, rather than consume, additional health care resources and optimally affect patient care. Diagnostic stewardship is needed to implement appropriate tests for the clinical setting and to direct testing toward appropriate patients. Antimicrobial stewardship is needed to ensure prompt appropriate clinical action to translate faster diagnostic test results in the laboratory into improved outcomes at the bedside. This minireview outlines the roles of diagnostic stewardship and antimicrobial stewardship in the implementation of rapid molecular infectious disease diagnostics.

Indexed as

Anti-Infective AgentsCommunicable DiseasesDrug UtilizationEarly DiagnosisHumansMicrobial Sensitivity TestsMolecular Diagnostic TechniquesTime FactorsAnti-Infective Agentsantimicrobial stewardshipappropriate use criteriadiagnostic stewardshipimplementationrapid diagnosticsutilization

Identifiers

PMID28031432
PMCPMC5328439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.