Evidence map›Paper›PMID 28031413›Full record

ArticleMolecular cancer research : MCR2017

Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors.

Monica E Wielgos, Rajani Rajbhandari, Tiffiny S Cooper, Shi Wei, Susan Nozell, Eddy S Yang

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Lin28/let-7 axis in breast cancer.Molecular biology reports · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Cancers · 2021
    Article
  10. Article
  11. PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs.International journal of molecular sciences · 2017
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Monica E WielgosDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Rajani RajbhandariDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Tiffiny S CooperDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Shi WeiDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama.
Susan NozellDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Eddy S YangDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama. eyang@uab.edu.
University of Alabama at Birmingham · US

Funding

UAB Rexinoids for Breast Cancer PreventionP50CA089019 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GRIZZLE, WILLIAM E. · 2000 to 2011
$26.0M
NCI NIH HHS P50 CA089019
6 · The paper itself

Abstract

HER2

Indexed as

Breast NeoplasmsCell Line, TumorCell ProliferationErb-b2 Receptor Tyrosine KinasesFemaleHumansMicroRNAsPoly (ADP-Ribose) Polymerase-1TransfectionUp-RegulationERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesMicroRNAsmirnlet7 microRNA, humanPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1

Identifiers

PMID28031413
PMCPMC5334184
OpenAlexW2564020005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.