Evidence map›Paper›PMID 28031405›Full record

Observational studyJournal of the American Society of Nephrology : JASN2017

A Variant of Peptide Transporter 2 Predicts the Severity of Porphyria-Associated Kidney Disease.

Dimitri Tchernitchko, Quentin Tavernier, Jérôme Lamoril, Caroline Schmitt, Neila Talbi, Said Lyoumi, Anne-Marie Robreau, Zoubida Karim, Laurent Gouya, Eric Thervet and 3 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Review
  6. Practical recommendations for biochemical and genetic diagnosis of the porphyrias.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  7. [Acute porphyria as a rare etiology of PRES]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Mechanisms of Neuronal Damage in Acute Hepatic Porphyrias.Diagnostics (Basel, Switzerland) · 2021
    Review
  17. Review
  18. The acute hepatic porphyrias.Translational gastroenterology and hepatology · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Dimitri TchernitchkoCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Quentin TavernierInstitut National pour la Santé et la Recherche Médicale (INSERM) U1147, Centre Universitaire des Saints Pères, Paris, France.
Jérôme LamorilCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Caroline SchmittCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Neila TalbiCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Said LyoumiInstitut National pour la Santé et la Recherche Médicale (INSERM) U1149, Center for Research on Inflammation (CRI), Site Bichat, Paris, France.
Anne-Marie RobreauCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Zoubida KarimInstitut National pour la Santé et la Recherche Médicale (INSERM) U1149, Center for Research on Inflammation (CRI), Site Bichat, Paris, France.
Laurent GouyaCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Eric ThervetInstitut National pour la Santé et la Recherche Médicale (INSERM) U1147, Centre Universitaire des Saints Pères, Paris, France.
Alexandre KarrasInstitut National pour la Santé et la Recherche Médicale (INSERM) U1147, Centre Universitaire des Saints Pères, Paris, France.
Hervé PuyCentre Français des Porphyries, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, Colombes, Paris, France.
Nicolas PalletInstitut National pour la Santé et la Recherche Médicale (INSERM) U1147, Centre Universitaire des Saints Pères, Paris, France; nicolas.pallet@aphp.fr.
Centre de Recherche sur l'Inflammation · FRInserm · FRUniversité Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FRDélégation Paris 5 · FRHôpital Louis-Mourier · FRLaboratory of Excellence GR-Ex · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CKD occurs in most patients with acute intermittent porphyria (AIP). During AIP,

Indexed as

Acute DiseaseAgedFemaleGenotypeHumansMaleMiddle AgedPorphyriasPrognosisRenal Insufficiency, ChronicSeverity of Illness IndexSymportershydrogen-coupled oligopeptide transporter PepT2SymportersAcute Intermittent Porphyriachronic kidney diseaseDelta-aminolevulinic acidPEPT2SLC15A2

Identifiers

PMID28031405
PMCPMC5461799
OpenAlexW2564053957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.