Evidence map›Paper›PMID 28031403›Full record

ArticleJournal of neurophysiology2017

Cutaneous neurturin overexpression alters mechanical, thermal, and cold responsiveness in physiologically identified primary afferents.

Michael P Jankowski, Kyle M Baumbauer, Ting Wang, Kathryn M Albers, Brian M Davis, H Richard Koerber

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Influencers in the Somatosensory System: Extrinsic Control of Sensory Neuron Phenotypes.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. GDNF, Neurturin, and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute to Inflammatory Bone Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael P JankowskiDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Kyle M BaumbauerDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ting WangDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Kathryn M AlbersDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Brian M DavisDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
H Richard KoerberDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania rkoerber@pitt.edu.
University of Pittsburgh · US

Funding

Peripheral Nerve Regeneration and Sensory Neuron PlasticityR01NS023725 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD · 1986 to 2017
$5.9M
Molecular genetic dissection of the spinal microcircuits of wind-upR01NS096705 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD, ROSS, SARAH ELIZABETH · 2016 to 2025
$5.1M
Role of Growth Factors in Persistent PainR01NS031826 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVIS, BRIAN M · 1993 to 2011
$3.5M
Characterization of epithelial-neural communicationR01AR069951 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERS, KATHRYN MARIE, DAVIS, BRIAN M · 2016 to 2020
$2.8M
NIAMS NIH HHS R01 AR069951NINDS NIH HHS R01 NS023725NINDS NIH HHS R01 NS031826NINDS NIH HHS R01 NS096705
6 · The paper itself

Abstract

Neurotrophic factors play an important role in the regulation of functional properties of sensory neurons under normal and pathological conditions. The GDNF family member neurturin is one such factor that has been linked to modulating responsiveness to peripheral stimuli. Neurturin binds to the GFRα2 receptor, a receptor found primarily in isolectin B

Indexed as

TemperatureAction PotentialsAfferent PathwaysAnalysis of VarianceAnimalsBiotinGanglia, SpinalGene Expression RegulationMiceMice, Inbred C57BLMice, TransgenicNerve FibersNeuronsNeurturinPhysical StimulationPsychophysicsBiotinneurobiotinNeurturinmechanical sensitivityneurturinnociceptorspainthermal responsiveness

Identifiers

PMID28031403
PMCPMC5349329
OpenAlexW2561723244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.