Evidence map›Paper›PMID 28031342›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Transcriptional Classification and Functional Characterization of Human Airway Macrophage and Dendritic Cell Subsets.

Vineet I Patel, J Leland Booth, Elizabeth S Duggan, Steven Cate, Vicky L White, David Hutchings, Susan Kovats, Dennis M Burian, Mikhail Dozmorov, Jordan P Metcalf

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Simulated poultry-house PMApplied and environmental microbiology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Dendritic Cells: Multifunctional Roles in Host Defenses toJournal of fungi (Basel, Switzerland) · 2023
    Review
  10. Review
  11. Innate Pulmonary Phagocytes and Their Interactions with PathogenicJournal of fungi (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Macrophage Mediated Immunomodulation DuringFrontiers in cellular and infection microbiology · 2022
    Review
  20. Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults.American journal of respiratory and critical care medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Vineet I PatelDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
J Leland BoothPulmonary and Critical Care Division, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Elizabeth S DugganPulmonary and Critical Care Division, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Steven CateDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Vicky L WhiteOffice of Aviation Medicine, Federal Aviation Administration, Oklahoma City, OK 73169.
David HutchingsCherokee Healthcare Services, Catoosa, OK 74015.
Susan KovatsDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.ORCID 0000-0001-5479-9952
Dennis M BurianOffice of Aviation Medicine, Federal Aviation Administration, Oklahoma City, OK 73169.ORCID 0000-0002-2664-4360
Mikhail DozmorovDepartment of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298.ORCID 0000-0002-0086-8358
Jordan P MetcalfDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104; jordan-metcalf@ouhsc.edu.
University of Oklahoma Health Sciences Center · USFederal Aviation Administration · USCherokee Nation · USOklahoma Medical Research Foundation · USVirginia Commonwealth University · US

Funding

Translation of immunologic technologies from basic research into pre-clinical nonU19AI062629 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI COGGESHALL, KENNETH MARK · 2004 to 2023
$56.2M
ZFC3H1 Regulation of Host Defense and Influenza A Virus PathogenesisP20GM103648 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI PATRAUCHAN, MARIANNA M. A. · 2013 to 2022
$22.3M
IRF4-Mediated Regulation of Lung Dendritic Cells During Viral InfectionR01HL119501 · NHLBI · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI KOVATS, SUSAN · 2014 to 2017
$1.7M
Antiviral Immunosuppression by Cigarette SmokeI01BX001937 · VA · OKLAHOMA CITY VA MEDICAL CENTER · PI METCALF, JORDAN PATRICK · 2015 to 2019
–
BLRD VA I01 BX001937NHLBI NIH HHS R01 HL119501NIAID NIH HHS U19 AI062629NIGMS NIH HHS P20 GM103648
6 · The paper itself

Abstract

The respiratory system is a complex network of many cell types, including subsets of macrophages and dendritic cells that work together to maintain steady-state respiration. Owing to limitations in acquiring cells from healthy human lung, these subsets remain poorly characterized transcriptionally and phenotypically. We set out to systematically identify these subsets in human airways by developing a schema of isolating large numbers of cells by whole-lung bronchoalveolar lavage. Six subsets of phagocytic APC (HLA-DR

Indexed as

AdultAgedAntigens, CDAntigens, CD1B7-2 AntigenCD83 AntigenDendritic CellsGene Expression ProfilingGlycoproteinsHumansImmunoglobulinsLipopolysaccharide ReceptorsLungMacrophagesMacrophages, AlveolarMembrane GlycoproteinsAntigens, CDAntigens, CD1B7-2 AntigenCD1C protein, humanCD83 AntigenGlycoproteinsImmunoglobulinsLipopolysaccharide ReceptorsMembrane Glycoproteins

Identifiers

PMID28031342
PMCPMC5262539
OpenAlexW2563031429

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.