Evidence map›Paper›PMID 28031262›Full record

ArticleInfection and immunity2017

Pseudomonas aeruginosa GroEL Stimulates Production of PTX3 by Activating the NF-κB Pathway and Simultaneously Downregulating MicroRNA-9.

Heesung Shin, Jisu Jeon, Jung-Hoon Lee, Shouguang Jin, Un-Hwan Ha

Abstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  8. Article
  9. Article
  10. Article
  11. International journal of molecular sciences · 2021
    Article
  12. HSP70-Homolog DnaK ofInternational journal of molecular sciences · 2020
    Article
  13. Article
  14. Protective Effect of Recombinant Proteins ofFrontiers in cellular and infection microbiology · 2020
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Heesung ShinDepartment of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea.
Jisu JeonDepartment of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea.
Jung-Hoon LeeDepartment of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea.
Shouguang JinState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China.
Un-Hwan HaDepartment of Biotechnology and Bioinformatics, Korea University, Sejong, Republic of Korea haunhwan@korea.ac.kr.
Korea University · KRState Key Laboratory of Medicinal Chemical Biology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As one of the first lines of host defense, monocytes play important roles in clearing infected microbes. The defensive response is triggered by recognition of diverse microbial moieties, including released factors, which modulate host immune responses to establish a harsh environment for clinically important bacterial pathogens. In this study, we found that the expression of PTX3, a soluble form of pattern recognition receptor, was induced by infection with live

Indexed as

Signal TransductionBacterial ProteinsCell LineCells, CulturedC-Reactive ProteinGene Expression RegulationHumansMicroRNAsNF-kappa BPentraxinsPhagocytosisPseudomonas aeruginosaPseudomonas InfectionsSerum Amyloid P-ComponentToll-Like Receptor 4Bacterial ProteinsC-Reactive ProteinMicroRNAsMIRN92 microRNA, humanNF-kappa BPentraxinsSerum Amyloid P-ComponentToll-Like Receptor 4GroELmicroRNA-9NF-κBPseudomonas aeruginosaPTX3

Identifiers

PMID28031262
PMCPMC5328476
OpenAlexW2560996623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.