Evidence map›Paper›PMID 28031261›Full record

ArticleInfection and immunity2017

Copper Is a Host Effector Mobilized to Urine during Urinary Tract Infection To Impair Bacterial Colonization.

Amanda N Hyre, Kylie Kavanagh, Nancy D Kock, George L Donati, Sargurunathan Subashchandrabose

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. A Putative Multicopper Oxidase Encoded byInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. A cynomolgus monkeyInfection and immunity · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Control of nutrient metal availability during host-microbe interactions: beyond nutritional immunity.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amanda N HyreDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Kylie KavanaghDepartment of Pathology/Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Nancy D KockDepartment of Pathology/Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
George L DonatiDepartment of Chemistry, Wake Forest University, Winston-Salem, North Carolina, USA.
Sargurunathan SubashchandraboseDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA ssubashc@wakehealth.edu.
Wake Forest University · US

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Vervet Research Colony as a Biomedical ResourceP40OD010965 · OD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Matthew Jorgensen · 2012 to 2026
$14.6M
NCATS NIH HHS UL1 TR001420NIH HHS P40 OD010965
6 · The paper itself

Abstract

Urinary tract infection (UTI) is a major global infectious disease affecting millions of people annually. Human urinary copper (Cu) content is elevated during UTI caused by uropathogenic

Indexed as

Host-Pathogen InteractionsAnimalsBacterial LoadBacteriuriaCeruloplasminCopperDisease Models, AnimalEnzyme ActivationHumansIonsMicePrimatesStress, PhysiologicalUrinary TractCeruloplasminCopperIonsceruloplasmincopperUPECurinary tract infectionuropathogenic E. coliUTI

Identifiers

PMID28031261
PMCPMC5328488
OpenAlexW2566671575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.