ArticleCerebral cortex (New York, N.Y. : 1991)2017
Evidence for an Optimal Algorithm Underlying Signal Combination in Human Visual Cortex.
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Binocular summation revisited: Beyond √2.Psychological bulletin · 2018Pooled it
- Signal combination in flutter vibration perception.PloS one · 2026Article
- Binocular combination in the autonomic nervous system.PloS one · 2026Article
- Multisensory suppressive neurons can implement Bayesian-like nonlinearly weighted sensory combination.Frontiers in human neuroscience · 2026Article
- Significant Age-Related Visual Declines but Preserved Binocular Summation of Contrast Sensitivity and Visual Acuity Across Adulthood.Investigative ophthalmology & visual science · 2025Article
- Interocular suppression in chromoluminance patterns measured with SSVEP.Journal of vision · 2025Article
- Binocular integration of chromatic and luminance signals.Journal of vision · 2024Article
- Different rules for binocular combination of luminance flicker in cortical and subcortical pathways.eLife · 2023Article
- Local Interactions between Steady-State Visually Evoked Potentials at Nearby Flickering Frequencies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Steady-state measures of visual suppression.PLoS computational biology · 2021Article
- Neural markers of suppression in impaired binocular vision.NeuroImage · 2021Article
- Article
- Effect of Cross-Orientation Normalization on Different Neural Measures in Macaque Primary Visual Cortex.Cerebral cortex communications · 2021Article
- Contrast Normalization Accounts for Binocular Interactions in Human Striate and Extra-striate Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Interaction between steady-state visually evoked potentials at nearby flicker frequencies.Scientific reports · 2020Article
- Binaural summation of amplitude modulation involves weak interaural suppression.Scientific reports · 2020Article
- Binocular summation for reflexive eye movements.Journal of vision · 2018Article
- Perception of global image contrast involves transparent spatial filtering and the integration and suppression of local contrasts (not RMS contrast).Royal Society open science · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
How does the cortex combine information from multiple sources? We tested several computational models against data from steady-state electroencephalography (EEG) experiments in humans, using periodic visual stimuli combined across either retinal location or eye-of-presentation. A model in which signals are raised to an exponent before being summed in both the numerator and the denominator of a gain control nonlinearity gave the best account of the data. This model also predicted the pattern of responses in a range of additional conditions accurately and with no free parameters, as well as predicting responses at harmonic and intermodulation frequencies between 1 and 30 Hz. We speculate that this model implements the optimal algorithm for combining multiple noisy inputs, in which responses are proportional to the weighted sum of both inputs. This suggests a novel purpose for cortical gain control: implementing optimal signal combination via mutual inhibition, perhaps explaining its ubiquity as a neural computation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.