Evidence map›Paper›PMID 28031170›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Influence of sex on hyperfiltration in patients with uncomplicated type 1 diabetes.

Marko Škrtić, Yuliya Lytvyn, Petter Bjornstad, Heather N Reich, James W Scholey, Paul Yip, Etienne B Sochett, Bruce Perkins, David Z I Cherney

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  3. Article
  4. Review
  5. Glomerular hyperfiltration: part 2-clinical significance in children.Pediatric nephrology (Berlin, Germany) · 2023
    Review
  6. Article
  7. Low birthweight is associated with lower glomerular filtration rate in middle-aged mainly healthy women.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Article
  8. Review
  9. Sex differences in renal ammonia metabolism.American journal of physiology. Renal physiology · 2021
    Article
  10. Review
  11. Sex differences in diabetes and kidney disease: mechanisms and consequences.American journal of physiology. Renal physiology · 2019
    Review
  12. Article
  13. Comparison of diabetic nephropathy between male and female eNOSAmerican journal of physiology. Renal physiology · 2019
    Article
  14. Recent advances in sex differences in kidney function.American journal of physiology. Renal physiology · 2019
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Marko ŠkrtićDepartment of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Yuliya LytvynDepartment of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Petter BjornstadDepartment of Pediatric Endocrinology, Barbara Davis Center for Diabetes University of Colorado School of Medicine, Aurora, CO.
Heather N ReichDepartment of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
James W ScholeyDepartment of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Paul YipUniversity Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Etienne B SochettDepartment of Pediatrics, Division of Endocrinology, Sickkids Hospital, University of Toronto, Toronto, Ontario, Canada.
Bruce PerkinsDepartment of Medicine, Division of Endocrinology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
David Z I CherneyDepartment of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada; david.cherney@uhn.ca.
University of Toronto · CAMount Sinai Hospital · CASickKids Foundation · CAToronto General Hospital · CAUniversity of Colorado Denver · US

Funding

Training Program in Diabetes ResearchT32DK063687 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Andrea Steck · 2002 to 2026
$5.2M
CIHRNIDDK NIH HHS T32 DK063687
6 · The paper itself

Abstract

The aim of this analysis was to examine sex-based differences in renal segmental resistances in healthy controls (HCs) and patients with type 1 diabetes (T1D). We hypothesized that hyperfiltration-an early hemodynamic abnormality associated with diabetic nephropathy-would disproportionately affect women with T1D, thereby attenuating protection against the development of renal complications. Glomerular hemodynamic parameters were evaluated in HC (

Indexed as

Glomerular Filtration RateHemodynamicsAdultCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetic NephropathiesFemaleHumansKidney GlomerulusMaleModels, BiologicalRenal Plasma Flow, EffectiveRetrospective StudiesRisk FactorsSex FactorsVascular Resistanceglomerular hemodynamicshyperfiltrationsextype 1 diabetes

Identifiers

PMID28031170
PMCPMC6109809
OpenAlexW2565199160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.