Evidence map›Paper›PMID 28031061›Full record

ArticleInfection control and hospital epidemiology2017

Which Comorbid Conditions Should We Be Analyzing as Risk Factors for Healthcare-Associated Infections?

Anthony D Harris, Lisa Pineles, Deverick Anderson, Keith F Woeltje, William E Trick, Keith S Kaye, Deborah S Yokoe, Ann-Christine Nyquist, David P Calfee, Surbhi Leekha

Open access · greenAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Observational
  3. Electronically Available Patient Claims Data Improve Models for Comparing Antibiotic Use Across Hospitals: Results From 576 US Facilities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  4. Electronically Available Comorbidities Should Be Used in Surgical Site Infection Risk Adjustment.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Anthony D Harris1University of Maryland School of Medicine,Baltimore,Maryland.
Lisa Pineles1University of Maryland School of Medicine,Baltimore,Maryland.
Deverick Anderson2Duke University Medical Center,Department of Medicine,Division of Infectious Diseases,Durham,North Carolina.
Keith F Woeltje4Department of Medicine,Washington University Medical Center,St Louis,Missouri.
William E Trick5Rush University Medical Center,Chicago,Illinois.
Keith S Kaye7Division of Infectious Diseases,Detroit Medical Center,Wayne State University,Detroit,Michigan.
Deborah S Yokoe8Department of Medicine,Brigham & Women's Hospital,Boston,Massachusetts.
Ann-Christine Nyquist9Children's Hospital Colorado,Aurora,Colorado.
David P Calfee10Weill Cornell Medicine,New York,New York.
Surbhi Leekha1University of Maryland School of Medicine,Baltimore,Maryland.
University of Maryland, Baltimore · USBJC HealthCare · USBrigham and Women's Hospital · USDetroit Medical Center · USDuke Medical Center · USRush University Medical Center · USUniversity of Colorado Denver · USWeill Cornell Medicine · US

Funding

Use of electronic data to improve risk adjustment for hospital infection ratesR01HS022291 · AHRQ · UNIVERSITY OF MARYLAND BALTIMORE · PI HARRIS, ANTHONY D · 2013 to 2016
$1.3M
AHRQ HHS R01 HS022291
6 · The paper itself

Abstract

OBJECTIVE To determine which comorbid conditions are considered causally related to central-line associated bloodstream infection (CLABSI) and surgical-site infection (SSI) based on expert consensus. DESIGN Using the Delphi method, we administered an iterative, 2-round survey to 9 infectious disease and infection control experts from the United States. METHODS Based on our selection of components from the Charlson and Elixhauser comorbidity indices, 35 different comorbid conditions were rated from 1 (not at all related) to 5 (strongly related) by each expert separately for CLABSI and SSI, based on perceived relatedness to the outcome. To assign expert consensus on causal relatedness for each comorbid condition, all 3 of the following criteria had to be met at the end of the second round: (1) a majority (>50%) of experts rating the condition at 3 (somewhat related) or higher, (2) interquartile range (IQR)≤1, and (3) standard deviation (SD)≤1. RESULTS From round 1 to round 2, the IQR and SD, respectively, decreased for ratings of 21 of 35 (60%) and 33 of 35 (94%) comorbid conditions for CLABSI, and for 17 of 35 (49%) and 32 of 35 (91%) comorbid conditions for SSI, suggesting improvement in consensus among this group of experts. At the end of round 2, 13 of 35 (37%) and 17 of 35 (49%) comorbid conditions were perceived as causally related to CLABSI and SSI, respectively. CONCLUSIONS Our results have produced a list of comorbid conditions that should be analyzed as risk factors for and further explored for risk adjustment of CLABSI and SSI. Infect Control Hosp Epidemiol 2017;38:449-454.

Indexed as

ComorbidityBacteremiaCatheter-Related InfectionsConsensusCross InfectionDelphi TechniqueHumansRisk FactorsSurgical Wound InfectionUnited States

Identifiers

PMID28031061
PMCPMC5684869
OpenAlexW2561625416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.