Evidence map›Paper›PMID 28031023›Full record

ArticleBMC medical research methodology2016

Can longitudinal generalized estimating equation models distinguish network influence and homophily? An agent-based modeling approach to measurement characteristics.

Kori Sauser Zachrison, Theodore J Iwashyna, Achamyeleh Gebremariam, Meghan Hutchins, Joyce M Lee

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Article in BMC medical research methodology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kori Sauser ZachrisonDepartment of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Zero Emerson Place Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA. ksauser@mgh.harvard.edu.
Theodore J IwashynaVA HSR&D Center of Excellence, Ann Arbor, MI, USA.
Achamyeleh GebremariamDivision of Pediatric Endocrinology, Child Health Evaluation and Research Unit (CHEAR), Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Meghan HutchinsCenter for the Study of Complex Systems, University of Michigan, Ann Arbor, MI, USA.
Joyce M LeeDivision of Pediatric Endocrinology, Child Health Evaluation and Research Unit (CHEAR), Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.

Funding

Identifying novel system-level factors associated with the quality of acute stroke care deliveryK08HS024561 · AHRQ · MASSACHUSETTS GENERAL HOSPITAL · PI ZACHRISON, KORILYN SAUSER · 2016 to 2020
$784k
Childhood Obesity and Type 2 Diabetes Trends: A Life Course AnalysisK08DK082386 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JOYCE · 2008 to 2012
$755k
The structure and outcomes of critical care transfer networkK08HL091249 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IWASHYNA, THEODORE J · 2008 to 2012
$661k
AHRQ HHS K08 HS024561NHLBI NIH HHS K08 HL091249NIDDK NIH HHS K08 DK082386
6 · The paper itself

Abstract

backgroundConnected individuals (or nodes) in a network are more likely to be similar than two randomly selected nodes due to homophily and/or network influence. Distinguishing between these two influences is an important goal in network analysis, and generalized estimating equation (GEE) analyses of longitudinal dyadic network data are an attractive approach. It is not known to what extent such regressions can accurately extract underlying data generating processes. Therefore our primary objective is to determine to what extent, and under what conditions, does the GEE-approach recreate the actual dynamics in an agent-based model.

methodsWe generated simulated cohorts with pre-specified network characteristics and attachments in both static and dynamic networks, and we varied the presence of homophily and network influence. We then used statistical regression and examined the GEE model performance in each cohort to determine whether the model was able to detect the presence of homophily and network influence.

resultsIn cohorts with both static and dynamic networks, we find that the GEE models have excellent sensitivity and reasonable specificity for determining the presence or absence of network influence, but little ability to distinguish whether or not homophily is present.

conclusionsThe GEE models are a valuable tool to examine for the presence of network influence in longitudinal data, but are quite limited with respect to homophily.

Indexed as

Models, StatisticalSocial SupportData Interpretation, StatisticalHumansRegression AnalysisGEE ModelsNetwork AnalysisNetwork Influence

Identifiers

PMID28031023
PMCPMC5192582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.