Evidence map›Paper›PMID 28030821›Full record

ArticleOncotarget2017

Vitamin D status among long-term survivors of testicular cancer.

Giuseppe Schepisi, Silvia De Padova, Emanuela Scarpi, Cristian Lolli, Giorgia Gurioli, Cecilia Menna, Salvatore L Burgio, Lorena Rossi, Valentina Gallà, Valentina Casadio and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Vitamin D Deficiency in Testicular Cancer Survivors: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  2. Long-term toxicity of cisplatin in germ-cell tumor survivors.Annals of oncology : official journal of the European Society for Medical Oncology · 2017
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Vitamin D and Male Fertility: An Updated Review.The world journal of men's health · 2020
    Review
  8. Article
  9. Review
  10. Article
  11. The role of vitamin D in male fertility: A focus on the testis.Reviews in endocrine & metabolic disorders · 2017
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Giuseppe SchepisiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Silvia De PadovaIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Emanuela ScarpiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Cristian LolliIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Giorgia GurioliIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Cecilia MennaIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Salvatore L BurgioIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Lorena RossiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Valentina GallàIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Valentina CasadioIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Samanta SalviIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Vincenza ConteducaIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Ugo De GiorgiIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 40 I-47014 Meldola, FC, Italy.
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A correlation between disturbances in hormone levels and the onset of metabolic disorders has been reported in long-term survivors of testicular cancer (TC).We evaluated serum vitamin D levels and other biological parameters in a consecutive series of 61 long-term (≥3 years) unilateral TC survivors with a median a follow-up of 4 years and in a cohort of healthy males. Deficient vitamin D levels were observed in 10 (17%) of the 58 long-term unilateral TC survivors but were not reported in healthy males (p=.019, Fisher test). Median vitamin D levels were 18.6 ug/L in 58 assessable TC survivors and 23.6 ug/L in 40 healthy males (p=.031). In univariate logistic regression analysis, TC diagnosis was associated with inadequate levels of vitamin D (p=.047). Vitamin D levels were lower when follow-up was > 10 years, albeit this difference was not statistically significant (p=.074). Long-term (especially > 10 years) TC survivors may have difficulty maintaining optimal vitamin D levels. Larger studies are needed to better characterize vitamin D status and possible correlations with premature hormonal aging reported in long-term TC survivors.

Indexed as

Cancer SurvivorsAdultAgedBiomarkersCase-Control StudiesCombined Modality TherapyComorbidityHumansMaleMiddle AgedNeoplasms, Germ Cell and EmbryonalNeoplasm StagingRisk FactorsTesticular NeoplasmsVitamin DYoung AdultBiomarkersVitamin D25-hydroxyvitamin Dgerm cell tumorhypogonadismtesticular cancer survivorstestosterone

Identifiers

PMID28030821
PMCPMC5482697
OpenAlexW2563726138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.