Mitochondrial Donation - Clearing the Final Regulatory Hurdle in the United Kingdom.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Mitochondrial dysfunction in neurodegenerative disorders: Potential therapeutic application of mitochondrial transfer to central nervous system-residing cells.Journal of translational medicine · 2023
   Review
2. Mitochondrial transplantation: opportunities and challenges in the treatment of obesity, diabetes, and nonalcoholic fatty liver disease.Journal of translational medicine · 2022
   Review
3. The Present and Future of Mitochondrial-Based Therapeutics for Eye Disease.Translational vision science & technology · 2021
   Article
4. Mitochondrial disease genetics update: recent insights into the molecular diagnosis and expanding phenotype of primary mitochondrial disease.Current opinion in pediatrics · 2018
   Review
5. Mitochondrial Replacement Techniques : Examining Collective Representation in Emerging Technologies Governance.Journal of bioethical inquiry · 2018
   Article
6. Mitochondrial Disease: Advances in clinical diagnosis, management, therapeutic development, and preventative strategies.Current genetic medicine reports · 2018
   Article
7. Scientific and Ethical Issues in Mitochondrial Donation.The New bioethics : a multidisciplinary journal of biotechnology and the body · 2018
   Article
8. Inherited eye-related disorders due to mitochondrial dysfunction.Human molecular genetics · 2017
   Review
9. Experience from the First Live-Birth Derived From Oocyte Nuclear Transfer as a Treatment Strategy for Mitochondrial Diseases.Journal of molecular and genetic medicine : an international journal of biomedical research · 2017
   Article
10. Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications.Stem cells international · 2017
    Review

Corrections and comments

• Comment on
  Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.2016

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as