Evidence map›Paper›PMID 28029788›Full record

ArticleJournal of the American Chemical Society2017

Critical Aspects of Heme-Peroxo-Cu Complex Structure and Nature of Proton Source Dictate Metal-O(peroxo) Breakage versus Reductive O-O Cleavage Chemistry.

Suzanne M Adam, Isaac Garcia-Bosch, Andrew W Schaefer, Savita K Sharma, Maxime A Siegler, Edward I Solomon, Kenneth D Karlin

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A Bioinspired Nonheme FeJournal of the American Chemical Society · 2024
    Article
  5. Heme-copper and Heme OJournal of inorganic biochemistry · 2023
    Review
  6. Review
  7. Coupled transport of electrons and protons in a bacterial cytochromePhysical chemistry chemical physics : PCCP · 2020
    Article
  8. Heme-FeJournal of the American Chemical Society · 2020
    Article
  9. Article
  10. Article
  11. DFT FeInorganic chemistry · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suzanne M AdamJohns Hopkins University , Baltimore, Maryland 21218, United States.
Isaac Garcia-BoschJohns Hopkins University , Baltimore, Maryland 21218, United States.
Andrew W SchaeferDepartment of Chemistry, Stanford University , Stanford, California 94305, United States.
Savita K SharmaJohns Hopkins University , Baltimore, Maryland 21218, United States.
Maxime A SieglerJohns Hopkins University , Baltimore, Maryland 21218, United States.
Edward I SolomonDepartment of Chemistry, Stanford University , Stanford, California 94305, United States.
Kenneth D KarlinJohns Hopkins University , Baltimore, Maryland 21218, United States.ORCID 0000-0002-5675-7040

Funding

Structure/Function Correlations Over Copper EnzymesR01DK031450 · NIDDK · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 1986 to 2026
$8.7M
Heme/Copper and Heme/Nonheme Iron O(2) and NO ReactivityR01GM060353 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI KARLIN, KENNETH D. · 2000 to 2020
$5.9M
SPECTROSCOPIC STUDIES OF COPPER CLUSTERS IN PROTEINSR37DK031450 · NIDDK · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1994 to 2011
$5.7M
NIDDK NIH HHS R01 DK031450NIDDK NIH HHS R37 DK031450NIGMS NIH HHS R01 GM060353
6 · The paper itself

Abstract

The 4H

Indexed as

ProtonsCopperFerric CompoundsHemeHydrogen PeroxideKineticsOrganometallic CompoundsOxidation-ReductionOxygenQuantum TheoryCopperFerric CompoundsHemeHydrogen PeroxideOrganometallic CompoundsOxygenProtons

Identifiers

PMID28029788
PMCPMC5274545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.