Evidence map›Paper›PMID 28029159›Full record

ArticleNature genetics2016

Is a super-enhancer greater than the sum of its parts?

Noah Dukler, Brad Gulko, Yi-Fei Huang, Adam Siepel

Abstract readLetterComment
In one paragraph

Article in Nature genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Noah DuklerSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
Brad GulkoSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.ORCID 0000-0001-8366-589X
Yi-Fei HuangSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
Adam SiepelSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI John Edward Moses · 1987 to 2026
$118.9M
Computational methods for human genomic data integration: demography, selection,R01GM102192 · NIGMS · CORNELL UNIVERSITY · PI SIEPEL, ADAM CHARLES · 2013 to 2017
$1.7M
Factor-general characterization of dynamic transcriptional stress responsesR01HG007070 · NHGRI · CORNELL UNIVERSITY · PI LIS, JOHN T, SIEPEL, ADAM CHARLES · 2013 to 2015
$1.0M
NCI NIH HHS P30 CA045508NHGRI NIH HHS R01 HG007070NIGMS NIH HHS R01 GM102192
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enhancer Elements, GeneticTranscription, GeneticHumans

Identifiers

PMID28029159
PMCPMC5379849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.