ArticleJournal of gynecologic oncology2017
Computed tomography-based quantitative assessment of lower extremity lymphedema following treatment for gynecologic cancer.
Article in Journal of gynecologic oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Automated CT segmentation for lower extremity tissues in lymphedema evaluation using deep learning.European radiology · 2025Article
- Imaging and management of lymphedema in the era of precision oncology.The British journal of radiology · 2025Review
- Advances in etiology, pathophysiology, diagnosis, and management of lymphedema: a comprehensive review.Frontiers in medicine · 2025Review
- Current diagnostic and quantitative techniques in the field of lymphedema management: a critical review.Medical oncology (Northwood, London, England) · 2024Review
- Assessment Modalities for Lower Extremity Edema, Lymphedema, and Lipedema: A Scoping Review.Cureus · 2024Article
- The added value of SPECT/CT lymphoscintigraphy in the initial assessment of secondary extremity lymphedema patients.Scientific reports · 2023Article
- MRI-based volume measurement methods for staging primary lower extremity lymphedema: a single-center study of asymmetric volume difference-a diagnostic study.BMC musculoskeletal disorders · 2023Article
- Impact of Noise Level on the Accuracy of Automated Measurement of CT Number Linearity on ACR CT and Computational Phantoms.Journal of biomedical physics & engineering · 2023Article
- Diagnosis and Treatment of Post-Prostatectomy Lymphedema: What's New?Current oncology (Toronto, Ont.) · 2023Review
- Deep learning-based quantitative estimation of lymphedema-induced fibrosis using three-dimensional computed tomography images.Scientific reports · 2022Observational
- Temporal Changes in Subcutaneous Fibrosis in Patients with Lower Extremity Lymphedema Following Surgery for Gynecologic Cancer: A Computed Tomography-Based Quantitative Analysis.Diagnostics (Basel, Switzerland) · 2022Article
- Ultrasound Elastography Use in Lower Extremity Lymphedema: A Systematic Review of the Literature.Cureus · 2019Review
- 68Ga-NOTA-Evans Blue TOF PET/MR Lymphoscintigraphy Evaluation of the Severity of Lower Limb Lymphedema.Clinical nuclear medicine · 2019Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop an algorithmic quantitative skin and subcutaneous tissue volume measurement protocol for lower extremity lymphedema (LEL) patients using computed tomography (CT), to verify the usefulness of the measurement techniques in LEL patients, and to observe the structural characteristics of subcutaneous tissue according to the progression of LEL in gynecologic cancer.
methodsA program for algorithmic quantitative analysis of lower extremity CT scans has been developed to measure the skin and subcutaneous volume, muscle compartment volume, and the extent of the peculiar trabecular area with a honeycombed pattern. The CT venographies of 50 lower extremities from 25 subjects were reviewed in two groups (acute and chronic lymphedema).
resultsA significant increase in the total volume, subcutaneous volume, and extent of peculiar trabecular area with a honeycombed pattern except quantitative muscle volume was identified in the more-affected limb. The correlation of CT-based total volume and subcutaneous volume measurements with volumetry measurement was strong (correlation coefficient: 0.747 and 0.749, respectively). The larger extent of peculiar trabecular area with a honeycombed pattern in the subcutaneous tissue was identified in the more-affected limb of chronic lymphedema group.
conclusionCT-based quantitative assessments could provide objective volume measurements and information about the structural characteristics of subcutaneous tissue in women with LEL following treatment for gynecologic cancer.
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