Evidence map›Paper›PMID 28028837›Full record

ArticleThe Journal of physiology2017

A novel mechanism of tandem activation of ryanodine receptors by cytosolic and SR luminal Ca

Joshua T Maxwell, Lothar A Blatter

Open access · hybridAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Transcriptional factors in calcium mishandling and atrial fibrillation development.Pflugers Archiv : European journal of physiology · 2021
    Review
  6. Excitation-contraction coupling and calcium release in atrial muscle.Pflugers Archiv : European journal of physiology · 2021
    Review
  7. Triggered CaCirculation. Arrhythmia and electrophysiology · 2020
    Article
  8. Article
  9. Unique CaInternational journal of molecular sciences · 2018
    Review
  10. Axial Tubule Junctions Activate Atrial CaFrontiers in physiology · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. Ambiguous interactions between diastolic and SR CaThe Journal of general physiology · 2017
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joshua T MaxwellDepartment of Molecular Biophysics and Physiology, Rush University Medical Centre, Chicago, IL, 60612, USA.ORCID 0000-0001-7389-5245
Lothar A BlatterDepartment of Molecular Biophysics and Physiology, Rush University Medical Centre, Chicago, IL, 60612, USA.ORCID 0000-0003-3409-8678
Rush University Medical Center · US

Funding

Program AdministrationP01HL080101 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M · 2006 to 2015
$23.4M
Pathophysiological Regulation of Atrial Myocyte Excitation-Contraction Coupling and Calcium SignalingR01HL134781 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI BLATTER, LOTHAR A · 2017 to 2020
$1.5M
NHLBI NIH HHS P01 HL080101NHLBI NIH HHS R01 HL134781
6 · The paper itself

Abstract

key pointsIn atrial myocytes excitation-contraction coupling is strikingly different from ventricle because atrial myocytes lack a transverse tubule membrane system: Ca ABSTRACT: In atrial myocytes Ca

Indexed as

AnimalsCalciumCalcium SignalingCytosolExcitation Contraction CouplingHeart AtriaHeart VentriclesMaleMyocardial ContractionMyocytes, CardiacRabbitsRyanodine Receptor Calcium Release ChannelSarcolemmaSarcoplasmic ReticulumSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPasesatrial myocytesexcitation-contraction couplingSR Ca release

Identifiers

PMID28028837
PMCPMC5471506
OpenAlexW2566241028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.