Evidence map›Paper›PMID 28028819›Full record

Trial reportActa neurologica Scandinavica2017

A pilot randomized controlled trial comparing effectiveness of prism glasses, visual search training and standard care in hemianopia.

F J Rowe, E J Conroy, E Bedson, E Cwiklinski, A Drummond, M García-Fiñana, C Howard, A Pollock, T Shipman, C Dodridge and 5 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Acta neurologica Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 9 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 9 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Guideline
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  5. Audio-visual stimulation for visual compensatory functions in stroke survivors with visual field defect: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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  8. Interventions for visual field defects in people with stroke.The Cochrane database of systematic reviews · 2019
    Pooled it
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  10. A randomized controlled trial of Scanning Eye trAining as a Rehabilitation Choice for Hemianopia after stroke (SEARCH).International journal of stroke : official journal of the International Stroke Society · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

F J RoweDepartment of Health Services Research, University of Liverpool, Liverpool, UK.
E J ConroyDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
E BedsonClinical Trials Research Unit, University of Liverpool, Liverpool, UK.
E CwiklinskiClinical Trials Research Unit, University of Liverpool, Liverpool, UK.
A DrummondSchool of Health Sciences, University of Nottingham, Nottingham, UK.
M García-FiñanaDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
C HowardDepartment of Orthoptics, Salford Royal NHS Foundation Trust, Manchester, UK.
A PollockNursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK.
T ShipmanDepartment of Orthoptics, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
C DodridgeDepartment of Orthoptics, Oxford University Hospitals NHS Trust, Oxford, UK.
C MacIntoshDepartment of Orthoptics, Oxford University Hospitals NHS Trust, Oxford, UK.
S JohnsonEye Clinic Impact Team, Royal National Institute for the Blind, Birmingham, UK.
C NoonanDepartment of Ophthalmology, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
G BartonDepartment of Elderly Care, Warrington and Halton Hospitals NHS Foundation Trust, Warrington, UK.
C SackleyDivision of Health and Social Care, King's College, London, UK.
University of Liverpool · GBOxford University Hospitals NHS Trust · GBGlasgow Caledonian University · GBKing's College School · GBRoyal National Institute of Blind · GBSalford Royal NHS Foundation Trust · GBSheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Nottingham · GBWarrington and Halton Teaching Hospitals NHS Foundation Trust · GB

Funding

Chief Scientist Office NMAHP2
6 · The paper itself

Abstract

objectivePilot trial to compare prism therapy and visual search training, for homonymous hemianopia, to standard care (information only).

methodsProspective, multicentre, parallel, single-blind, three-arm RCT across fifteen UK acute stroke units.

participantsStroke survivors with homonymous hemianopia.

interventionsArm a (Fresnel prisms) for minimum 2 hours, 5 days per week over 6 weeks. Arm b (visual search training) for minimum 30 minutes, 5 days per week over 6 weeks. Arm c (standard care-information only). INCLUSION CRITERIA: Adult stroke survivors (>18 years), stable hemianopia, visual acuity better than 0.5 logMAR, refractive error within ±5 dioptres, ability to read/understand English and provide consent. OUTCOMES: Primary outcomes were change in visual field area from baseline to 26 weeks and calculation of sample size for a definitive trial. Secondary measures included Rivermead Mobility Index, Visual Function Questionnaire 25/10, Nottingham Extended Activities of Daily Living, Euro Qual, Short Form-12 questionnaires and Radner reading ability. Measures were post-randomization at baseline and 6, 12 and 26 weeks. RANDOMIZATION: Randomization block lists stratified by site and partial/complete hemianopia. BLINDING: Allocations disclosed to patients. Primary outcome assessor blind to treatment allocation.

resultsEighty-seven patients were recruited: 27-Fresnel prisms, 30-visual search training and 30-standard care; 69% male; mean age 69 years (SD 12). At 26 weeks, full results for 24, 24 and 22 patients, respectively, were compared to baseline. Sample size calculation for a definitive trial determined as 269 participants per arm for a 200 degree

conclusionsNo significant change occurred for area of visual field area across arms over follow-up. Visual search training had significant improvement in vision-related quality of life. Prism therapy produced adverse events in 69%. Visual search training results warrant further investigation.

Indexed as

Activities of Daily LivingEyeglassesQuality of LifeAdultAgedAged, 80 and overFemaleHemianopsiaHumansMaleMiddle AgedPilot ProjectsProspective StudiesSingle-Blind MethodStrokeStroke Rehabilitationhomonymous hemianopiapilot trialprism therapyrandomized controlled trialstandard carestrokevisual search training

Identifiers

PMID28028819
OpenAlexW2563303012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.