ArticleJournal of cardiovascular translational research2017
A Study of Coronary Bifurcation Shape in a Normal Population.
Article in Journal of cardiovascular translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review and meta-analysis of Murray's law in the coronary arterial circulation.American journal of physiology. Heart and circulatory physiology · 2024Pooled it
- State-of-the-Art Review on Finite Element Analysis Applied to Ultrathin-Strut Drug-Eluting Stents: Examining the Present and Looking Ahead to the Future.Bioengineering (Basel, Switzerland) · 2026Review
- Optimising Generalisable Deep Learning Models for CT Coronary Segmentation: A Multifactorial Evaluation.Journal of imaging informatics in medicine · 2026Article
- High-intensity helical flow: a double-edged sword in coronary artery haemodynamics.Royal Society open science · 2025Article
- Assessing left main bifurcation anatomy and haemodynamics as a potential surrogate for disease risk in suspected coronary artery disease without stenosis.Scientific reports · 2025Article
- VM-CAGSeg: a vessel structure-aware state space model for coronary artery segmentation in angiography images.Frontiers in medicine · 2025Article
- [Hemodynamics simulation and analysis of left coronary artery aneurysms with concomitant stenosis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Annotated computed tomography coronary angiogram images and associated data of normal and diseased arteries.Scientific data · 2023Article
- Customizable Angioplasty Balloon-Forming Machine: Towards Precision Medicine in Coronary Bifurcation Lesion Interventions.Journal of cardiovascular translational research · 2022Article
- Percutaneous coronary intervention of bifurcation lesions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Article
- 3D Printing for Cardiovascular Applications: From End-to-End Processes to Emerging Developments.Annals of biomedical engineering · 2021Review
- How to ValidateFrontiers in medical technology · 2021Article
- Approximating the maximum tibial coverage in total knee arthroplasty does not necessarily result in implant malrotation.Scientific reports · 2020Observational
- Effect of Coronary Artery Bifurcation Angle on Atherosclerotic Lesion Localization Distance to the Bifurcation Site.Journal of the Saudi Heart Association · 2020Article
- Morphological analysis of sigmoid sinus anatomy: clinical applications to neurotological surgery.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2019Article
- Topologic and Hemodynamic Characteristics of the Human Coronary Arterial Circulation.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During percutaneous coronary intervention, stents are placed in narrowings of the arteries to restore normal blood flow. Despite improvements in stent design, deployment techniques and drug-eluting coatings, restenosis and stent thrombosis remain a significant problem. Population stent design based on statistical shape analysis may improve clinical outcomes. Computed tomographic (CT) coronary angiography scans from 211 patients with a zero calcium score, no stenoses and no intermediate artery, were used to create statistical shape models of 446 major coronary artery bifurcations (left main, first diagonal and obtuse marginal and right coronary crux). Coherent point drift was used for registration. Principal component analysis shape scores were tested against clinical risk factors, quantifying the importance of recognised shape features in intervention including size, angles and curvature. Significant differences were found in (1) vessel size and bifurcation angle between the left main and other bifurcations; (2) inlet and curvature angle between the right coronary crux and other bifurcations; and (3) size and bifurcation angle by sex. Hypertension, smoking history and diabetes did not appear to have an association with shape. Physiological diameter laws were compared, with the Huo-Kassab model having the best fit. Bifurcation coronary anatomy can be partitioned into clinically meaningful modes of variation showing significant shape differences. A computational atlas of normal coronary bifurcation shape, where disease is common, may aid in the design of new stents and deployment techniques, by providing data for bench-top testing and computational modelling of blood flow and vessel wall mechanics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.