Evidence map›Paper›PMID 28028692›Full record

ArticleJournal of cardiovascular translational research2017

In Vitro Hydrodynamic Assessment of a New Transcatheter Heart Valve Concept (the TRISKELE).

Benyamin Rahmani, Spyros Tzamtzis, Rose Sheridan, Michael J Mullen, John Yap, Alexander M Seifalian, Gaetano Burriesci

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Innovation and Challenges in Materials for Transcatheter Aortic Valves.Journal of cardiovascular translational research · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Biomimetic Polyurethanes in Tissue Engineering.Biomimetics (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. In Vitro Durability and Stability Testing of a Novel Polymeric Transcatheter Aortic Valve.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2020
    Article
  18. Review
  19. In vitro hemodynamic assessment of a novel polymeric transcatheter aortic valve.Journal of the mechanical behavior of biomedical materials · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benyamin RahmaniCardiovascular Engineering Laboratory, UCL Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.ORCID http://orcid.org/0000-0002-8062-6737
Spyros TzamtzisCardiovascular Engineering Laboratory, UCL Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.
Rose SheridanCardiovascular Engineering Laboratory, UCL Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.
Michael J MullenBarts Health NHS Trust, University College London Hospital, London, UK.
John YapBarts Health NHS Trust, University College London Hospital, London, UK.
Alexander M SeifalianNanoRegMed Ltd, London, UK.
Gaetano BurriesciCardiovascular Engineering Laboratory, UCL Mechanical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK. g.burriesci@ucl.ac.uk.

Funding

Department of Health J003
6 · The paper itself

Abstract

This study presents the in vitro hydrodynamic assessment of the TRISKELE, a new system suitable for transcatheter aortic valve implantation (TAVI), aiming to mitigate the procedural challenges experienced with current technologies. The TRISKELE valve comprises three polymeric leaflet and an adaptive sealing cuff, supported by a novel fully retrievable self-expanding nitinol wire frame. Valve prototypes were manufactured in three sizes of 23, 26, and 29 mm by automated dip-coating of a biostable polymer, and tested in a hydrodynamic bench setup in mock aortic roots of 21, 23, 25, and 27 mm annulus, and compared to two reference valves suitable for equivalent implantation ranges: Edwards SAPIEN XT and Medtronic CoreValve. The TRISKELE valves demonstrated a global hydrodynamic performance comparable or superior to the controls with significant reduction in paravalvular leakage. The TRISKELE valve exhibits enhanced anchoring and improved sealing. The valve is currently under preclinical investigation.

Indexed as

Heart Valve ProsthesisHemodynamicsSelf Expandable Metallic StentsAlloysAortic ValveHumansHydrodynamicsMaterials TestingProsthesis DesignStainless SteelTranscatheter Aortic Valve ReplacementAlloysnitinolStainless SteelPolymeric leafletsPreclinical assessmentSelf-expanding stentTAVI

Identifiers

PMID28028692
PMCPMC5437138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.