Evidence map›Paper›PMID 28028558›Full record

ReviewCurrent genetics2017

mRNA length-sensing in eukaryotic translation: reconsidering the "closed loop" and its implications for translational control.

Mary K Thompson, Wendy V Gilbert

Open access · bronzeAbstract readReview
In one paragraph

Review in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Length-Dependent Translation Efficiency of ER-Destined Proteins.Current issues in molecular biology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Rebirth of the translational machinery: The importance of recycling ribosomes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Mary K ThompsonDepartment of Biology, Massachusetts Institute of Technology, Cambridge, USA.
Wendy V GilbertDepartment of Biology, Massachusetts Institute of Technology, Cambridge, USA. wgilbert@mit.edu.
Massachusetts Institute of Technology · US

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Ribosome Specialization and RegulationR01GM094303 · NIGMS · YALE UNIVERSITY · PI GILBERT, WENDY VICTORIA · 2012 to 2016
$1.5M
NIGMS NIH HHS R01 GM094303NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

Most eukaryotic mRNAs are recruited to the ribosome by recognition of a 5' m

Indexed as

Nucleic Acid ConformationProtein BiosynthesisEukaryotic CellsRibosomal ProteinsRibosomesRNA, MessengerRibosomal ProteinsRNA, MessengerClosed loopRACK1RibosomeTranslation

Identifiers

PMID28028558
PMCPMC5484751
OpenAlexW2565392373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.