Evidence map›Paper›PMID 28028548›Full record

ArticlemSystems

Spatial Molecular Architecture of the Microbial Community of a

Neha Garg, Yi Zeng, Anna Edlund, Alexey V Melnik, Laura M Sanchez, Hosein Mohimani, Alexey Gurevich, Vivian Miao, Stefan Schiffler, Yan Wei Lim and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The Tripartite LichenMicroorganisms · 2023
    Article
  6. Review
  7. Imaging mass spectrometry reveals complex lipid distributions acrossJournal of mass spectrometry and advances in the clinical lab · 2022
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Recent advances in tools to map the microbiome.Current opinion in biomedical engineering · 2021
    Article
  15. Article
  16. Lichens - growing greenhousesMicrobial cell (Graz, Austria) · 2021
    Article
  17. The Lichens' Microbiota, Still a Mystery?Frontiers in microbiology · 2021
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Neha GargSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA.
Yi ZengDepartment of Chemistry and Biochemistry, University of California, San Diego, California, USA.
Anna EdlundGenomic Medicine, J. Craig Venter Institute, La Jolla, California, USA.
Alexey V MelnikSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA.
Laura M SanchezSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID 0000-0001-9223-7977
Hosein MohimaniDepartment of Computer Science and Engineering, University of California San Diego, La Jolla, California, USA.
Alexey GurevichCenter for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia.
Vivian MiaoDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Stefan SchifflerSCiLS GmbH, Bremen, Germany.
Yan Wei LimDepartment of Biology, San Diego State University, San Diego, California, USA.
Tal Luzzatto-KnaanSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA.
Shengxin CaiNatural Products Discovery Group, Department of Chemistry and Biochemistry, Institute for Natural Products Applications and Research Technologies, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma, USA.
Forest RohwerDepartment of Biology, San Diego State University, San Diego, California, USA.
Pavel A PevznerDepartment of Computer Science and Engineering, University of California San Diego, La Jolla, California, USA.
Robert H CichewiczNatural Products Discovery Group, Department of Chemistry and Biochemistry, Institute for Natural Products Applications and Research Technologies, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma, USA.
Theodore AlexandrovSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA; SCiLS GmbH, Bremen, Germany; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Pieter C DorresteinSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, California, USA; Department of Chemistry and Biochemistry, University of California, San Diego, California, USA; Center for Computational Mass Spectrometry and Department of Computer Science and Engineering, University of California San Diego, La Jolla, California, USA.

Funding

UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4M
TrainingP41GM103484 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PEVZNER, PAVEL A · 2012 to 2018
$8.7M
Synapt ion mobility mass spectrometerS10RR029121 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORRESTEIN, PIETER C · 2011 to 2011
$802k
NCRR NIH HHS S10 RR029121NIGMS NIH HHS K12 GM068524NIGMS NIH HHS P41 GM103484
6 · The paper itself

Abstract

Microbes are commonly studied as individual species, but they exist as mixed assemblages in nature. At present, we know very little about the spatial organization of the molecules, including natural products that are produced within these microbial networks. Lichens represent a particularly specialized type of symbiotic microbial assemblage in which the component microorganisms exist together. These composite microbial assemblages are typically comprised of several types of microorganisms representing phylogenetically diverse life forms, including fungi, photosymbionts, bacteria, and other microbes. Here, we employed matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) imaging mass spectrometry to characterize the distributions of small molecules within a

Indexed as

lichenmass spectrometrymetagenomicsmicrobial assemblagesnatural products

Identifiers

PMID28028548
PMCPMC5183598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.