Evidence map›Paper›PMID 28028546›Full record

ArticlemSphere

Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay.

Lora H Rigatti, Tuna Toptan, Joseph T Newsome, Patrick S Moore, Yuan Chang

Open access · goldAbstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  5. Pathogen Prevalence Estimates and Diagnostic Methodology Trends in Laboratory Mice and Rats from 2003 to 2020.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lora H RigattiDivision of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Cancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.
Tuna ToptanCancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.
Joseph T NewsomeDivision of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Cancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.
Patrick S MooreCancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8132-858X
Yuan ChangCancer Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.
UPMC Hillman Cancer Center · USUniversity of Pittsburgh · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0M
Discovery and Characterization of New Human Cancer VirusesR35CA197463 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOORE, PATRICK S. · 2016 to 2022
$6.2M
Role of a New Polyomavirus in Merkel Cell CarcinomaR01CA136806 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOORE, PATRICK S. · 2009 to 2015
$3.0M
Protein Biomarkers for a New Human Polyomavirus in AIDS-related MalignanciesR01CA136363 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOORE, PATRICK S. · 2008 to 2015
$2.3M
Transcriptomic and Proteomic Approaches to Discovering Viral Causes for Human HemR01CA170354 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHANG, YUAN · 2012 to 2015
$1.3M
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA136363NCI NIH HHS R01 CA136806NCI NIH HHS R01 CA170354NCI NIH HHS R35 CA197463
6 · The paper itself

Abstract

Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including cancers, particularly in immune-suppressed hosts. A novel polyomavirus, designated rat polyomavirus 2 (RatPyV2), was identified from a breeding colony of rats having X-linked severe combined immunodeficiency. Using a human panpolyomavirus immunohistochemistry test (P-PIT), RatPyV2 was initially detected in the parotid salivary gland of a colony member. Rolling circle amplification using DNA from harderian and parotid glands identified a novel 5.1-kb polyomavirus genome closely related to human Washington University (WU) and Karolinska Institute (KI) and vole polyomaviruses but notably divergent from

Indexed as

epitheliotropismimmune suppressioninclusion bodyKIVlaboratory animalspolyomavirusP-PITsimian virus 40WUVX-SCID

Identifiers

PMID28028546
PMCPMC5177731
OpenAlexW2565580807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.