ArticleScience advances2016
General and programmable synthesis of hybrid liposome/metal nanoparticles.
Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 76 citations in OpenAlex.
- Intraluminal Gold Nanoparticle-Loaded Liposomes Enable High-Resolution Nanoscale Mapping of Intracellular Delivery Pathways.ACS applied nano materials · 2026Article
- Confined Synthesis of Axial Chlorine Coordinated Single-Atom Nanozyme Within Liposomes for Sensitive Immunoassay.Nano-micro letters · 2026Article
- Exploring the Coating of Gold Nanoparticles with Lipids.Nanomaterials (Basel, Switzerland) · 2025Article
- A state-of-the-art review of the recent advances of theranostic liposome hybrid nanoparticles in cancer treatment and diagnosis.Cancer cell international · 2025Review
- Recent Progress of Preparation Strategies in Organic Nanoparticles for Cancer Phototherapeutics.Molecules (Basel, Switzerland) · 2023Review
- Modular super-assembly of hierarchical superstructures from monomicelle building blocks.Science advances · 2022Article
- Design and synthesis of gold nanostars-based SERS nanotags for bioimaging applications.Nanotheranostics · 2022Review
- Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy.Pharmaceutics · 2021Review
- CuO Bionanocomposite with Enhanced Stability and Antibacterial Activity against Extended-Spectrum Beta-Lactamase Strains.Materials (Basel, Switzerland) · 2021Article
- Au@Ag Core@Shell Nanoparticles Synthesized with Rumex hymenosepalus as Antimicrobial Agent.Nanoscale research letters · 2021Article
- The Combination of Liposomes and Metallic Nanoparticles as Multifunctional Nanostructures in the Therapy and Medical Imaging-A Review.International journal of molecular sciences · 2021Review
- Smart Stimuli-Responsive Liposomal Nanohybrid Systems: A Critical Review of Theranostic Behavior in Cancer.Pharmaceutics · 2021Review
- The Application of Nanotechnology for the Diagnosis and Treatment of Brain Diseases and Disorders.Frontiers in bioengineering and biotechnology · 2021Review
- Vitamin C and Cardiovascular Disease: An Update.Antioxidants (Basel, Switzerland) · 2020Review
- Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death.Nature communications · 2020Article
- Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting.PloS one · 2020Article
- Fast Semiconductor-Metal Bidirectional Transition by Flame Chemical Vapor Deposition.ACS omega · 2019Article
- Silver Nanoparticles: Synthesis and Application for Nanomedicine.International journal of molecular sciences · 2019Review
- Hybrid lipid-nanoparticle complexes for biomedical applications.Journal of materials chemistry. B · 2019Review
- Peptide/Cas9 nanostructures for ribonucleoprotein cell membrane transport and gene edition.Chemical science · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrid liposome/metal nanoparticles are promising candidate materials for biomedical applications. However, the poor selectivity and low yield of the desired hybrid during synthesis pose a challenge. We designed a programmable liposome by selective encoding of a reducing agent, which allows self-crystallization of metal nanoparticles within the liposome to produce stable liposome/metal nanoparticles alone. We synthesized seven types of liposome/monometallic and more complex liposome/bimetallic hybrids. The resulting nanoparticles are tunable in size and metal composition, and their surface plasmon resonance bands are controllable in visible and near infrared. Owing to outer lipid bilayer, our liposome/Au nanoparticle shows better colloidal stability in biologically relevant solutions as well as higher endocytosis efficiency than gold nanoparticles without the liposome. We used this hybrid in intracellular imaging of living cells via surface-enhanced Raman spectroscopy, taking advantage of its improved physicochemical properties. We believe that our method greatly increases the utility of metal nanoparticles in in vivo applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.