ArticleOpen access Macedonian journal of medical sciences2016
Cigarette Smoking and Oxidative Stress in Patients with Coronary Artery Disease.
Article in Open access Macedonian journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- A chronic whole cigarette smoke extract model reveals redox-mitochondrial adaptation in human lung epithelial and organoid models.Experimental & molecular medicine · 2026Article
- A Comparison of Cigarette Smoking Effects on Intervertebral Disc Cell Metabolism in a Rat Tissue Model.Annals of biomedical engineering · 2026Article
- Oxidative balance score and all-cause mortality among hypertensive individuals.Journal of global health · 2025Article
- Interaction Between Smoking and Olfactory Function on Frailty: A Population-Based Cross-Sectional Study.Health science reports · 2025Article
- The Dual Role of Oxidative Stress in Atherosclerosis and Coronary Artery Disease: Pathological Mechanisms and Diagnostic Potential.Antioxidants (Basel, Switzerland) · 2025Review
- Smoking and endometriosis: A narrative review.Tobacco induced diseases · 2025Review
- Evaluating SORT1 and SESN1 genes expression in peripheral blood mononuclear cells and oxidative stress status in patients with coronary artery disease.BMC genomic data · 2024Article
- Young users of electronic cigarettes exhibit reduced cardiorespiratory fitness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Integrated use of biofeedback and neurofeedback techniques in treating pathological conditions and improving performance: a narrative review.Frontiers in neuroscience · 2024Review
- Oxidative stress and food as medicine.Frontiers in nutrition · 2024Review
- Oxidative Stress in Pregnancy.Biomolecules · 2023Review
- Diabetes- versus smoking-related thrombo-inflammation in peripheral artery disease.Cardiovascular diabetology · 2023Review
- A Transcriptomic Analysis of Smoking-Induced Gene Expression Alterations in Coronary Artery Disease Patients.International journal of molecular sciences · 2023Article
- The Role of Inflammation in Age-Related Macular Degeneration-Therapeutic Landscapes in Geographic Atrophy.Cells · 2023Review
- Cigarette Smoke-Induced Respiratory Response: Insights into Cellular Processes and Biomarkers.Antioxidants (Basel, Switzerland) · 2023Review
- Non-esterified fatty acids and risk of peripheral artery disease in older adults: The cardiovascular health study.Atherosclerosis · 2023Article
- Effect of Aerobic Exercise on Arterial Stiffness in Individuals with Different Smoking Statuses.International journal of sports medicine · 2023Article
- Does combined training of biofeedback and neurofeedback affect smoking status, behavior, and longitudinal brain plasticity?Frontiers in behavioral neuroscience · 2023Article
- Association of oxidative stress, programmed cell death, GSTM1 gene polymorphisms, smoking and the risk of lung carcinogenesis: A two-step Mendelian randomization study.Frontiers in physiology · 2023Article
- Increased Levels of Autoantibodies against ROS-Modified Proteins in Depressed Individuals with Decrease in Antibodies against SARS-CoV-2 Antigen (S1-RBD).Current issues in molecular biology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine whether cigarette smoking, as a risk factor for CAD, affects (anti)oxidant status. MATERIAL AND
methodsThe study included patients with CAD, divided according to their smoking status and the number of cigarettes smoked during a day. Biological markers of oxidative stress (concentration of oxidants and activity of antioxidant enzymes) were measured in all subjects.
resultsThe study included 300 patients with CAD, (average age of 63 ± 11 years), predominantly males. Of the total, 34.0% were active smokers, 23.0% were former smokers, and 43.0% were non-smokers. Most of the active smokers smoked 1-20 cigarettes/day. In terms of concentration of oxidants (MDA and HP) there was not a significant difference between smokers versus non-smokers. As for the activity of antioxidant enzymes (SOD, CAT and GPX), a statistically significant difference was found in the activity of GPX among the active smokers with CAD and the non-smokers with CAD (p = 0.039).
conclusionSmoking as a risk factor for CAD is closely associated with increased oxidative stress, and the number of cigarettes smoked plays an important role in increasing the level of oxidative damage and reducing antioxidant defence.
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