ArticleOpen access Macedonian journal of medical sciences2016
Assessment of Increase in Aortic and Carotid Intimal Medial Thickness in Type 1 Diabetic Patients.
Article in Open access Macedonian journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Aortic intima media thickness in children and adolescents with type 1 diabetes: A systematic review.Pediatric diabetes · 2022Pooled it
- Vascular Aging: Assessment and Intervention.Clinical interventions in aging · 2023Review
- Association between Proinflammatory Markers, Leukocyte-Endothelium Interactions, and Carotid Intima-Media Thickness in Type 2 Diabetes: Role of Glycemic Control.Journal of clinical medicine · 2020Article
- Copeptin as a Biomarker of Atherosclerosis in Type 1 Diabetic Patients.Open access Macedonian journal of medical sciences · 2019Article
- Osteopontin for Early Detection of Microvascular and Macrovascular Type 1 Diabetic Complication.Open access Macedonian journal of medical sciences · 2019Article
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Authors and funding
3 authors.
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Abstract
aimTo assess aortic and carotid intima-media thickness (aIMT and cIMT) in diabetic patients. PATIENTS AND
methodsThe study included 75 type 1 diabetic patients and 30 age and sex matched healthy volunteer. A blood sample was taken for analysis of HbA1 and lipid profile and the urine sample was taken for analysis of albumin/creatinine ratio. aIMT and cIMT via ultrasound were also done.
resultscIMT & aIMT were significantly higher in diabetics. aIMT was found to be significantly higher than cIMT in diabetic patients (0.72 ± 0.11 vs. 0.52 ± 0.06, P = 0.0001). Ten of our patients (14%) with normal cIMT revealed significantly increased aIMT. aIMT had a significant positive correlation with age of patients, waist/hip ratio & cIMT.
conclusionDiabetic patients had increased aIMT and cIMT with a relatively greater increase in the aIMT than in the cIMT. Because atherosclerosis begins first in the intima of the aorta, these data suggest that the aIMT might provide the best currently available noninvasive marker of preclinical atherosclerosis in children. We recommend frequent follow up of diabetic patients for early detection of diabetic complication.
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