Evidence map›Paper›PMID 28028355›Full record

ReviewWorld journal of gastroenterology2016

From blood to breath: New horizons for esophageal cancer biomarkers.

Roger Yazbeck, Simone E Jaenisch, David I Watson

Abstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Development of aScientific reports · 2019
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  16. Alternatives to Traditional Per-Oral Endoscopy for Screening.Gastrointestinal endoscopy clinics of North America · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roger YazbeckRoger Yazbeck, Simone E Jaenisch, David I Watson, Department of Surgery, Flinders Centre for Innovation in Cancer, Flinders University, South Australia 5042, Australia.
Simone E JaenischRoger Yazbeck, Simone E Jaenisch, David I Watson, Department of Surgery, Flinders Centre for Innovation in Cancer, Flinders University, South Australia 5042, Australia.
David I WatsonRoger Yazbeck, Simone E Jaenisch, David I Watson, Department of Surgery, Flinders Centre for Innovation in Cancer, Flinders University, South Australia 5042, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer is a lethal cancer encompassing adenocarcinoma and squamous cell carcinoma sub-types. The global incidence of esophageal cancer is increasing world-wide, associated with the increased prevalence of associated risk factors. The asymptomatic nature of disease often leads to late diagnosis and five-year survival rates of less than 15%. Current diagnostic tools are restricted to invasive and costly endoscopy and biopsy for histopathology. Minimally and non-invasive biomarkers of esophageal cancer are needed to facilitate earlier detection and better clinical management of patients. This paper summarises recent insights into the development and clinical validation of esophageal cancer biomarkers, focussing on circulating markers in the blood, and the emerging area of breath and odorant biomarkers.

Indexed as

AdenocarcinomaAutoantibodiesBiomarkers, TumorBreath TestsCarcinoembryonic AntigenCarcinoma, Squamous CellEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaHumansMicroRNAsTumor Suppressor Protein p53Volatile Organic CompoundsAutoantibodiesBiomarkers, TumorCarcinoembryonic AntigenMicroRNAsTP53 protein, humanTumor Suppressor Protein p53Volatile Organic CompoundsBiomarkerBreath analysisCancerEsophageal cancerMicroRNANon-invasive

Identifiers

PMID28028355
PMCPMC5155166

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.