ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2017
Function and evolution of a Lotus japonicus AP2/ERF family transcription factor that is required for development of infection threads.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes.The New phytologist · 2026Article
- OROSOMUCOID PROTEIN 1 regulation of sphingolipid synthesis is required for nodulation in Aeschynomene evenia.Plant physiology · 2024Article
- Innovation and appropriation in mycorrhizal and rhizobial Symbioses.The Plant cell · 2022Article
- Auxin methylation byProceedings of the National Academy of Sciences of the United States of America · 2022Article
- The effects of ERN1 on gene expression during early rhizobial infection inFrontiers in plant science · 2022Article
- Structure and Development of the Legume-Rhizobial Symbiotic Interface in Infection Threads.Cells · 2021Review
- Assessment of Polygala paniculata (Polygalaceae) characteristics for evolutionary studies of legume-rhizobia symbiosis.Journal of plant research · 2020Article
- Allelic Variants for Candidate Nitrogen Fixation Genes Revealed by Sequencing in Red Clover (International journal of molecular sciences · 2019Article
- ERN1 and CYCLOPS coordinately activate NIN signaling to promote infection thread formation in Lotus japonicus.Journal of plant research · 2019Article
- NIN Acts as a Network Hub Controlling a Growth Module Required for Rhizobial Infection.Plant physiology · 2019Article
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- LACK OF SYMBIONT ACCOMMODATION controls intracellular symbiont accommodation in root nodule and arbuscular mycorrhizal symbiosis in Lotus japonicus.PLoS genetics · 2019Article
- Transcription factors network in root endosymbiosis establishment and development.World journal of microbiology & biotechnology · 2018Review
- Dynamics of Ethylene Production in Response to Compatible Nod Factor.Plant physiology · 2018Article
- DistinctFrontiers in plant science · 2018Article
- Article
- Cytokinin Biosynthesis Promotes Cortical Cell Responses during Nodule Development.Plant physiology · 2017Article
- Respiratory Burst Oxidase Homolog Gene A Is Crucial forFrontiers in plant science · 2017Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legume-rhizobium symbiosis is achieved by two major events evolutionarily acquired: root hair infection and organogenesis. Infection thread (IT) development is a distinct element for rhizobial infection. Through ITs, rhizobia are efficiently transported from infection foci on root hairs to dividing meristematic cortical cells. To unveil this process, we performed genetic screening using Lotus japonicus MG-20 and isolated symbiotic mutant lines affecting nodulation, root hair morphology, and IT development. Map-based cloning identified an AP2/ERF transcription factor gene orthologous to Medicago truncatula ERN1. LjERN1 was activated in response to rhizobial infection and depended on CYCLOPS and NSP2. Legumes conserve an ERN1 homolog, ERN2, that functions redundantly with ERN1 in M. truncatula. Phylogenetic analysis showed that the lineages of ERN1 and ERN2 genes originated from a gene duplication event in the common ancestor of legume plants. However, genomic analysis suggested the lack of ERN2 gene in the L. japonicus genome, consistent with Ljern1 mutants exhibited a root hair phenotype that is observed in ern1/ern2 double mutants in M. truncatula. Molecular evolutionary analysis suggested that the nonsynonymous/synonymous rate ratios of legume ERN1 genes was almost identical to that of non-legume plants, whereas the ERN2 genes experienced a relaxed selective constraint.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.