Evidence map›Paper›PMID 28027454›Full record

ReviewBosnian journal of basic medical sciences2017

Apocrine carcinoma of the breast: A brief update on the molecular features and targetable biomarkers.

Semir Vranic, Rebecca Feldman, Zoran Gatalica

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Bosnian journal of basic medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07613151 (NAPOLI), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07613151 recruitingnot on this mapstarted 2026, after this paper: background citation

NAPOLI: Negative/Low Hormone Receptor and APOcrine Lobular Invasive Breast Carcinoma - A Real-World International Cohort Study

TypeobservationalSponsorIstituto Oncologico Veneto IRCCSRan2026 to 2027Enrolled250ConditionsLobular Breast CarcinomaArmsUpfront Breast Surgery, Adjuvant Radiotherapy, Endocrine Therapy, Chemotherapy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. A Preliminary Investigation into Search and Matching for Tumor Discrimination in World Health Organization Breast Taxonomy Using Deep Networks.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Apocrine lesions of the breast.Virchows Archiv : an international journal of pathology · 2022
    Review
  13. Article
  14. Histology of Luminal Breast Cancer.Breast care (Basel, Switzerland) · 2020
    Review
  15. Observational
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Semir VranicDepartment of Pathology, University of Sarajevo Clinical Center. semir.vranic@gmail.com.
Rebecca Feldman
Zoran Gatalica
Caris Life Sciences (United States) · USLevine Cancer Institute · USUniversity of Sarajevo · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apocrine carcinoma of the breast is a rare, primary breast cancer characterized by the apocrine morphology, estrogen receptor-negative and androgen receptor-positive profile with a frequent overexpression of Her-2/neu protein (~30%). Apart from the Her-2/neu target, advanced and/or metastatic apocrine carcinomas have limited treatment options. In this review, we briefly describe and discuss the molecular features and new theranostic biomarkers for this rare mammary malignancy. The importance of comprehensive profiling is highlighted due to synergistic and potentially antagonistic molecular events in the individual patients.

Indexed as

Antineoplastic AgentsBiomarkers, TumorBreastBreast NeoplasmsErb-b2 Receptor Tyrosine KinasesEstrogen Receptor alphaFemaleGene Expression Regulation, NeoplasticHumansImmunohistochemistryIn Situ HybridizationNeoplasm InvasivenessNeoplasm MetastasisPTEN PhosphohydrolaseReceptors, AndrogenSignal TransductionAntineoplastic AgentsAR protein, humanBiomarkers, TumorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesESR1 protein, humanEstrogen Receptor alphaPTEN PhosphohydrolasePTEN protein, humanReceptors, Androgen

Identifiers

PMID28027454
PMCPMC5341783
OpenAlexW2564489383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.