Evidence map›Paper›PMID 28026929›Full record

ArticleBioconjugate chemistry2017

Near-Infrared Quantum Dot and

Yiming Zhao, Travis M Shaffer, Sudeep Das, Carlos Pérez-Medina, Willem J M Mulder, Jan Grimm

Open access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 36 citations in OpenAlex.

  1. Radiolabeled AgScientific reports · 2026
    Article
  2. Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Radionuclide-Activated Nanomaterials and Their Biomedical Applications.Angewandte Chemie (International ed. in English) · 2019
    Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yiming ZhaoTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States.
Travis M ShafferDepartment of Chemistry, Hunter College and the Graduate Center of the City University of New York , New York, New York 10065, United States.
Sudeep Das
Carlos Pérez-MedinaTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States.
Willem J M MulderTranslational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States.
Jan GrimmPharmacology Program & Department of Radiology, Weill Cornell Medical College, Cornell University , New York, New York 10065, United States.ORCID 0000-0002-5282-9385
Icahn School of Medicine at Mount Sinai · USAmsterdam UMC Location University of Amsterdam · NLCornell University · USThe Graduate Center, CUNY · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
Theranostic HDL nanoparticles for inflammatory macrophages in atherosclerosisR01EB009638 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2009 to 2016
$4.6M
Cerenkov luminescence imaging for image-guided cancer surgeryR01CA183953 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2015 to 2019
$2.6M
PET/MRI to study nanotherapy in atherosclerosisR01HL125703 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2015 to 2018
$2.4M
Anti-inflammatory nanoparticle formulations to treat atherosclerosisR01HL118440 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM, NAHRENDORF, MATTHIAS · 2014 to 2017
$2.3M
A Surface Activable Nanoemulsion platform for Breast Cancer Diagnosis and TherapyR01CA155432 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2011 to 2015
$1.7M
Cerenkov-emission based nanosensors to detect biologic activities in vivoR01EB014944 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2012 to 2015
$1.6M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA155432NCI NIH HHS R01 CA183953NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL118440NHLBI NIH HHS R01 HL125703NIBIB NIH HHS R01 EB009638NIBIB NIH HHS R01 EB014944
6 · The paper itself

Abstract

Cerenkov luminescence (CL) is an emerging imaging modality that utilizes the light generated during the radioactive decay of many clinical used isotopes. Although it is increasingly used for background-free imaging and deep tissue photodynamic therapy, in vivo applications of CL suffer from limited tissue penetration. Here, we propose to use quantum dots (QDs) as spectral converters that can transfer the CL UV-blue emissions to near-infrared light that is less scattered or absorbed in vivo. Experiments on tissue phantoms showed enhanced penetration depth and increased transmitted intensity for CL in the presence of near-infrared (NIR) QDs. To realize this concept for in vivo imaging applications, we developed three types of NIR QDs and

Indexed as

AnimalsInfrared RaysIsotopesLuminescenceLuminescent MeasurementsMaleMiceMice, NudeNanoparticlesNeoplasmsOptical ImagingQuantum DotsSentinel Lymph NodeZirconiumIsotopesZirconium

Identifiers

PMID28026929
PMCPMC5311024
OpenAlexW2564378315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.