ArticleObesity (Silver Spring, Md.)2017
Initial body fat gain is related to brain volume changes in adolescents: A repeated-measures voxel-based morphometry study.
Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Central Obesity-related Brain Alterations Predict Cognitive Impairments in First Episode of Psychosis.Schizophrenia bulletin · 2026Observational
- Biobehavioral susceptibility for obesity in childhood: Behavioral, genetic and neuroimaging studies of appetite.Physiology & behavior · 2023Review
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- Obesity as a Risk Factor for Accelerated Brain Ageing in First-Episode Psychosis-A Longitudinal Study.Schizophrenia bulletin · 2021Article
- Structural Brain Changes Associated with Overweight and Obesity.Journal of obesity · 2021Review
- Impulsivity and body fat accumulation are linked to cortical and subcortical brain volumes among adolescents and adults.Scientific reports · 2019Article
- Interaction Effect of Sex and Body Mass Index on Gray Matter Volume.Frontiers in human neuroscience · 2019Article
- Volumetric gray matter measures of amygdala and accumbens in childhood overweight/obesity.PloS one · 2018Article
- Invasive and Non-invasive Stimulation of the Obese Human Brain.Frontiers in neuroscience · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectiveIndividuals with obesity versus those within a healthy weight range show brain volume differences, but it is unclear whether these differences reflect initial vulnerability factors or are secondary to weight gain.
methodsOne hundred sixty-two adolescents (M age = 15.3 ± 1.1; 81 females) with healthy weight were scanned at baseline. Sixty subjects (M baseline age: 15.2 ± 1.1; M follow-up age: 17.7 ± 1.2; 34 females) completed a second scan at 2- or 3-year follow-up. Voxel-based morphometry assessed global and regional gray matter (GM) and white matter (WM) volumes. Body fat percentage was assessed yearly over follow-up.
resultsBaseline global/regional GM/WM volume did not predict body fat gain over follow-up. Adolescents who gained body fat showed greater decreases in GM volume in the putamen compared with those who showed loss of body fat. Adolescents who gained body fat showed greater increases in WM volume in the anterior cingulate cortex compared with those who showed stability of or loss of body fat.
conclusionsBody fat gain versus stability and loss produce GM and WM volume changes, rather than baseline volumetric differences predicting body fat gain.
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Registered trials
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