Evidence map›Paper›PMID 28026757›Full record

ArticleIEEE transactions on medical imaging2017

Use of Sub-Ensembles and Multi-Template Observers to Evaluate Detection Task Performance for Data That are Not Multivariate Normal.

Xin Li, Abhinav K Jha, Michael Ghaly, Fatma E A Elshahaby, Jonathan M Links, Eric C Frey

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Can patient-specific acquisition protocol improve performance on defect detection task in myocardial perfusion SPECT?Proceedings of SPIE--the International Society for Optical Engineering · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE Guidelines).Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  9. Task-based assessment of binned and list-mode SPECT systems.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  10. A physics and learning-based transmission-less attenuation compensation method for SPECT.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin Li
Abhinav K Jha
Michael Ghaly
Fatma E A Elshahaby
Jonathan M Links
Eric C Frey

Funding

Dose Reduction in Pediatric Molecular ImagingR01EB013558 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI FREY, ERIC C., SGOUROS, GEORGE · 2012 to 2020
$4.6M
SIMULTANEOUS DUAL ISOTOPE SPECT W/ CROSS TALK CORRECTIONR01EB000288 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI FREY, ERIC C. · 2002 to 2011
$4.6M
End-to-End Optimization of SPECT Instrumentation, Acquisition, and ReconstructionR01EB016231 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI FREY, ERIC C., LINKS, JONATHAN M. · 2013 to 2016
$1.4M
NIBIB NIH HHS R01 EB000288NIBIB NIH HHS R01 EB013558NIBIB NIH HHS R01 EB016231
6 · The paper itself

Abstract

The Hotelling Observer (HO) is widely used to evaluate image quality in medical imaging. However, applying it to data that are not multivariate-normally (MVN) distributed is not optimal. In this paper, we apply two multi-template linear observer strategies to handle such data. First, the entire data ensemble is divided into sub-ensembles that are exactly or approximately MVN and homoscedastic. Next, a different linear observer template is estimated for and applied to each sub-ensemble. The first multi-template strategy, adapted from previous work, applies the HO to each sub-ensemble, calculates the area under the receiver operating characteristics curve (AUC) for each sub-ensemble, and averages the AUCs from all the sub-ensembles. The second strategy applies the Linear Discriminant (LD) to estimate test statistics for each sub-ensemble and calculates a single global AUC using the pooled test statistics from all the sub-ensembles. We show that this second strategy produces the maximum AUC when only shifting of the HO test statistics is allowed. We compared these strategies to the use of a single HO template for the entire data ensemble by applying them to the non-MVN data obtained from reconstructed images of a realistic simulated population of myocardial perfusion SPECT studies with the goal of optimizing the reconstruction parameters. Of the strategies investigated, the multi-template LD strategy yielded the highest AUC for any given set of reconstruction parameters. The optimal reconstruction parameters obtained by the two multi-template strategies were comparable and produced higher AUCs for each sub-ensemble than the single-template HO strategy.

Indexed as

Task Performance and AnalysisAlgorithmsArea Under CurveImage Processing, Computer-AssistedTomography, Emission-Computed, Single-Photon

Identifiers

PMID28026757
PMCPMC5496770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.