Evidence map›Paper›PMID 28026755›Full record

ArticleIEEE transactions on medical imaging2017

Passive Acoustic Mapping with the Angular Spectrum Method.

Costas D Arvanitis, Calum Crake, Nathan McDannold, Gregory T Clement

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Enhancing Passive Cavitation Imaging Using pIEEE transactions on bio-medical engineering · 2025
    Article
  3. Article
  4. Three-Dimensional Super-Resolution Passive Cavitation Mapping in Laser Lithotripsy.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Passive Cavitation Imaging Artifact Reduction Using Data-Adaptive Spatial Filtering.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. 3-D Transcranial Microbubble Cavitation Localization by Four Sensors.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  17. Review
  18. Time-Resolved Passive Cavitation Mapping Using the Transient Angular Spectrum Approach.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  19. Article
  20. mSOUND: An Open Source Toolbox for Modeling Acoustic Wave Propagation in Heterogeneous Media.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Costas D Arvanitis
Calum Crake
Nathan McDannold
Gregory T Clement
Harvard University · USCleveland Clinic · USGeorgia Institute of Technology · US

Funding

Ultrasound-induced blood-brain/tumor barrier disruption in brain metastasesP01CA174645 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI MCDANNOLD, NATHAN J., MCDANNOLD, NATHAN J. · 2013 to 2017
$6.2M
Controlled Delivery and Release of Chemotherapy in Brain Tumors with FUSR00EB016971 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI ARVANITIS, KONSTANTINOS-COSTAS · 2016 to 2018
$747k
NCI NIH HHS P01 CA174645NIBIB NIH HHS R00 EB016971
6 · The paper itself

Abstract

In the present proof of principle study, we evaluated the homogenous angular spectrum method for passive acoustic mapping (AS-PAM) of microbubble oscillations using simulated and experimental data. In the simulated data we assessed the ability of AS-PAM to form 3D maps of a single and multiple point sources. Then, in the two dimensional limit, we compared the 2D maps from AS-PAM with alternative frequency and time domain passive acoustic mapping (FD- and TD-PAM) approaches. Finally, we assessed the ability of AS-PAM to visualize microbubble activity in vivo with data obtained during 8 different experiments of FUS-induced blood-brain barrier disruption in 3 nonhuman primates, using a clinical MR-guided FUS system. Our in silico results demonstrate AS-PAM can be used to perform 3D passive acoustic mapping. 2D AS-PAM as compared to FD- PAM and TD-PAM is 10 and 200 times faster respectively and has similar sensitivity, resolution, and localization accuracy, even when the noise was 10-fold higher than the signal. In-vivo, the AS-PAM reconstructions of emissions at frequency bands pertinent to the different types of microbubble oscillations were also found to be more sensitive than TD-PAM. AS-PAM of harmonic-only components predicted safe blood-brain barrier disruption, whereas AS-PAM of broadband emissions correctly identified MR-evident tissue damage. The disparity (3.2 mm) in the location of the cavitation activity between the three methods was within their resolution limits. These data clearly demonstrate that AS-PAM is a sensitive and fast approach for PAM, thus providing a clinically relevant method to guide therapeutic ultrasound procedures.

Indexed as

AcousticsAnimalsMicrobubblesPrimatesSoundUltrasonic TherapyUltrasonography

Identifiers

PMID28026755
PMCPMC5565398
OpenAlexW2562718776

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.