ArticleCanadian journal of public health = Revue canadienne de sante publique2016
Determinants of vitamin D status in pregnant women and neonates.
Article in Canadian journal of public health = Revue canadienne de sante publique, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of prepregnancy body mass index on maternal micronutrient status: a meta-analysis.Scientific reports · 2021Pooled it
- Vitamin D Status of Infants of Mothers with Gestational Diabetes: Status at Birth and a Randomized Controlled Trial of Vitamin D Supplementation across Infancy.The Journal of nutrition · 2022Trial
- Vitamin D insufficiency in pregnant women from Lebanon: prevalence and key predictors.Reproductive health · 2025Article
- Vitamin D nutritional status in early pregnancy and its relationship with periconceptional multiple micronutrients supplementation.Asia Pacific journal of clinical nutrition · 2024Article
- Disparities in Vitamin D Status of Newborn Infants from a Diverse Sociodemographic Population in Montreal, Canada.The Journal of nutrition · 2022Article
- Sex-specific association of high maternal psychological stress during pregnancy on newborn birthweight.PloS one · 2022Article
- Knowledge, attitude, performance, and determinant factors of Vitamin D deficiency prevention behaviours among Iranian pregnant women.Archives of public health = Archives belges de sante publique · 2021Article
- Article
- Longitudinal Assessment of Vitamin D Status across Trimesters of Pregnancy.The Journal of nutrition · 2021Article
- Association between variants in vitamin D-binding protein gene and vitamin D deficiency among pregnant women in china.Journal of clinical laboratory analysis · 2020Article
- Association of Maternal Weight and Gestational Weight Gain with Maternal and Neonate Outcomes: A Prospective Cohort Study.Journal of clinical medicine · 2019Article
- Comparison of seasonal serum 25-hydroxyvitamin D concentrations among pregnant women in Mongolia and Boston.The Journal of steroid biochemistry and molecular biology · 2019Article
- Factors Associated with Serum 25-Hydroxyvitamin D Concentration in Two Cohorts of Pregnant Women in Southern Ontario, Canada.Nutrients · 2019Article
- Prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status.European journal of pediatrics · 2018Article
- Urinary BPA and Phthalate Metabolite Concentrations and Plasma Vitamin D Levels in Pregnant Women: A Repeated Measures Analysis.Environmental health perspectives · 2017Article
- Prenatal exposure to vitamin D from fortified margarine and risk of fractures in late childhood: period and cohort results from 222 000 subjects in the D-tect observational study.The British journal of nutrition · 2017Observational
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Authors and funding
7 authors.
Funding
Abstract
objectivesEvidence suggests a beneficial effect of vitamin D on perinatal health; however, low vitamin D status is prevalent in pregnant women and neonates. The objective was to determine factors that are associated with vitamin D status of mothers in early pregnancy and neonates.
methodsThe study comprised 1,635 pregnant women from Quebec City and Halifax, Canada, 2002-2010. Vitamin D status was based on the concentration of 25-hydroxy-vitamin D [25(OH)D] determined with a chemiluminescence immunoassay in maternal sera collected at a median of 15 weeks' gestation and in neonatal cord sera at delivery. A questionnaire with information on potential determinants was completed midpregnancy.
resultsA total of 44.8% of mothers and 24.4% of neonates had 25(OH)D concentrations <50 nmol/L. Adjusted mean (95% confidence interval) maternal 25(OH)D levels were higher in summer than in winter by 16.1 nmol/L (13.6-18.7), and in those in the highest versus the lowest category of education by 6.1 nmol/L (0.5-11.8), in BMI <25 kg/m2 versus BMI ≥35 kg/m2 by 8.2 nmol/L (4.0-12.3), and in the highest versus the lowest physical activity category by up to 9.5 nmol/L (2.9-16.1). Determinants of neonatal 25(OH)D levels were similar but also included maternal age, dairy intake, supplement use and 25(OH)D level.
conclusionThis study suggests that vitamin D status of pregnant women and/or neonates might be improved through supplementation, adequate dairy intake, a move towards a healthy pre-pregnancy body weight, and participation in physical activity. Controlled studies are needed to determine the effectiveness of interventions aimed at these factors.
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