Evidence map›Paper›PMID 28025976›Full record

ReviewCell research2017

Dendritic cell-based immunotherapy.

Rachel L Sabado, Sreekumar Balan, Nina Bhardwaj

Abstract readReview
In one paragraph

Review in Cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 474 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
474citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

474 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Overcoming Drug Resistance by Paclitaxel Resistance in Triple-Negative Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Review
  7. Green nanomedicine for cancer therapy.Chinese medical journal · 2026
    Review
  8. Review
  9. Review
  10. Adaptive resistance in cancer immunotherapy.Cellular & molecular immunology · 2026
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

414 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rachel L SabadoThe Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
Sreekumar BalanThe Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.
Nina BhardwajThe Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA.

Funding

Modulating anti-HIV immunity by plasmacytoid dendritic cellsR01AI081848 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BHARDWAJ, NINA · 2010 to 2021
$4.5M
Induction of Immunity by Non-Replicating HIV-1R37AI044628 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BHARDWAJ, NINA · 2004 to 2014
$4.2M
IN VIVO INDUCTION OF HIV SPECIFIC CTL BY DENDRITIC CELLSR01AI044628 · NIAID · ROCKEFELLER UNIVERSITY · PI BHARDWAJ, NINA · 1999 to 2003
$2.3M
Matrix metalloproteinase-2 modulates inflammation via TLR2R01CA180913 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BHARDWAJ, NINA · 2014 to 2018
$1.8M
NCI NIH HHS R01 CA180913NIAID NIH HHS R01 AI044628NIAID NIH HHS R01 AI081848NIAID NIH HHS R37 AI044628
6 · The paper itself

Abstract

Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for harnessing the potential of a patient's own immune system to eliminate tumor cells in metastatic hormone-refractory cancer. Overall, although many DC vaccines have been tested in the clinic and proven to be immunogenic, and in some cases associated with clinical outcome, there remains no consensus on how to manufacture DC vaccines. In this review we will discuss what has been learned thus far about human DC biology from clinical studies, and how current approaches to apply DC vaccines in the clinic could be improved to enhance anti-tumor immunity.

Indexed as

ImmunotherapyAnimalsAntigen PresentationAntigens, NeoplasmDendritic CellsHumansImmunityVaccinationAntigens, Neoplasm

Identifiers

PMID28025976
PMCPMC5223236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.