Evidence map›Paper›PMID 28025775›Full record

ReviewDermatology and therapy2017

Systemic Treatment of Adult Atopic Dermatitis: A Review.

Matteo Megna, Maddalena Napolitano, Cataldo Patruno, Alessia Villani, Anna Balato, Giuseppe Monfrecola, Fabio Ayala, Nicola Balato

Open access · goldAbstract readReview
In one paragraph

Review in Dermatology and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 153 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. 'High dose' vs. 'medium dose' UVA1 phototherapy in italian patients with severe atopic dermatitis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2019
    Trial
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Clinical Profile of Elderly Atopic Dermatitis in China.Clinical, cosmetic and investigational dermatology · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy.Tissue engineering and regenerative medicine · 2025
    Review
  18. Article
  19. Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matteo MegnaDepartment of Dermatology, University of Naples Federico II, Naples, Italy. mat24@libero.It.
Maddalena NapolitanoDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Cataldo PatrunoDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Alessia VillaniDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Anna BalatoDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Giuseppe MonfrecolaDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Fabio AyalaDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Nicola BalatoDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a common chronic inflammatory skin disease that predominantly affects children. However, it can persist in adulthood and/or start at older ages. Due to its chronic nature and frequently occurring relapses, AD has a substantial effect on patients' quality of life, often requiring long-term systemic treatment, especially in adult patients, who are more frequently refractory to adequate topical treatment with mid- to high-potent corticosteroids and/or calcineurin inhibitors. Therefore, treatment with systemic therapies is often needed to take control of the disease, prevent exacerbations and improve quality of life. However, data regarding systemic treatment effectiveness and long-term safety in adult patients with AD are insufficient. Indeed, standardized international guidelines are lacking, and the treatment approach widely differs among diverse countries. This review focuses on the use of systemic treatments in adult AD patients analyzing published literature.

Indexed as

Adult atopic dermatitisAtopic dermatitisBiologicsSystemic treatments

Identifiers

PMID28025775
PMCPMC5336433
OpenAlexW2566687596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.