Observational studyIndian journal of pediatrics2017
Bone Mineral Density in Celiac Disease.
Observational study in Indian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Micronutrient Deficiencies Associated with a Gluten-Free Diet in Patients with Celiac Disease and Non-Celiac Gluten or Wheat Sensitivity: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Vulnerability in Children with Celiac Disease: Findings from a Scoping Review.Children (Basel, Switzerland) · 2024Article
- Vitamin D: An Essential Nutrient in the Dual Relationship between Autoimmune Thyroid Diseases and Celiac Disease-A Comprehensive Review.Nutrients · 2024Review
- Factors Associated with Low Bone Mineral Density at the Time of Diagnosis in Children with Celiac DiseaseJournal of clinical research in pediatric endocrinology · 2023Article
- Investigation of the Factors Affecting Bone Mineral Density in Children with Celiac Disease.Pediatric gastroenterology, hepatology & nutrition · 2022Article
- Study of effect of gluten-free diet on vitamin D levels and bone mineral density in celiac disease patients.Journal of family medicine and primary care · 2022Article
- Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet.Nutrients · 2021Article
- Assessment of fractal dimension and panoramic radiomorphometric indices in women with celiac disease.Oral radiology · 2020Article
- Extra-Intestinal Manifestation of Celiac Disease in Children.Nutrients · 2018Review
- Celiac Disease in India - Status Update.Indian journal of pediatrics · 2017Article
- Bone modeling, remodeling, and skeletal health in children and adolescents: mineral accrual, assessment and treatment.Annals of pediatric endocrinology & metabolism · 2017Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo study bone mineral density (BMD) and standard serum biochemical indices among newly diagnosed and already diagnosed cases of Celiac Disease (CD) on gluten free diet for at least one year.
methodsThis hospital based analytic, observational study was done at a tertiary care centre, from April 2013 through June 2014. Thirty six children (20 females) with untreated CD at diagnosis (Group A) and 36 age and sex matched children on gluten-free diet for at least one year (Group B) were studied. Serum measurements of biochemical bone health indices and BMD, assessed by dual X-ray absorptiometry, were obtained.
resultsBMD Z-score was significantly low in newly diagnosed celiac patients. Patients on gluten free diet had higher BMD Z-score as compared to newly diagnosed patients (-2.02 vs. -0.65 respectively, p < 0.001). BMD Z-score was high in GI symptom patients as compared to non-GI symptom patients (-0.46+/-0.89 vs. - 0.88 = +/-0.94) in Group B. In female patients BMD Z-score was comparatively low as compared to male patients in both groups but difference was not significant. In Group A the mean serum calcium level was lower than the patients in Group B (8.72 + 0.73 vs. 9.34 + 0.65, p < 0.001). S. calcium levels were not correlated with bone mineral density (BMD) in both groups (P value >0.05).
conclusionsChildren with CD are at risk for reduced BMD. Strict gluten-free diet significantly improves bone mineralization. Early diagnosis and treatment of celiac disease during childhood may protect CD patients from osteoporosis.
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