Evidence map›Paper›PMID 28025660›Full record

ArticleWorld journal of urology2017

Low amplitude rhythmic contraction frequency in human detrusor strips correlates with phasic intravesical pressure waves.

Andrew F Colhoun, John E Speich, Lauren F Cooley, Eugene D Bell, R Wayne Barbee, Georgi Guruli, Paul H Ratz, Adam P Klausner

Open access · greenAbstract read
In one paragraph

Article in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. New Diagnostics for Male Lower Urinary Tract Symptoms.Current bladder dysfunction reports · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andrew F ColhounDepartment of Surgery/Division of Urology, VCU Medical Center, West Hospital, Virginia Commonwealth University School of Medicine, 7th Floor, Room 7205, 1200 East Broad Street, PO Box 980118, Richmond, VA, 23298-0118, USA.
John E SpeichDepartment of Mechanical and Nuclear Engineering, Virginia Commonwealth University School of Engineering, Richmond, VA, USA.
Lauren F CooleyVirginia Commonwealth University School of Medicine, Richmond, VA, USA.
Eugene D BellDepartment of Surgery/Division of Urology, VCU Medical Center, West Hospital, Virginia Commonwealth University School of Medicine, 7th Floor, Room 7205, 1200 East Broad Street, PO Box 980118, Richmond, VA, 23298-0118, USA.
R Wayne BarbeeDepartment of Emergency Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Georgi GuruliDepartment of Surgery/Division of Urology, VCU Medical Center, West Hospital, Virginia Commonwealth University School of Medicine, 7th Floor, Room 7205, 1200 East Broad Street, PO Box 980118, Richmond, VA, 23298-0118, USA.
Paul H RatzDepartments of Biochemistry and Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Adam P KlausnerDepartment of Surgery/Division of Urology, VCU Medical Center, West Hospital, Virginia Commonwealth University School of Medicine, 7th Floor, Room 7205, 1200 East Broad Street, PO Box 980118, Richmond, VA, 23298-0118, USA. adam.klausner@vcuhealth.org.
Virginia Commonwealth University · USVirginia Commonwealth University Medical Center · US

Funding

The Detrusor Tension Sensor: A Model for Novel Cystometrics in Overactive BladderR01DK101719 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI KLAUSNER, ADAM PHILIP, SPEICH, JOHN E · 2015 to 2023
$2.4M
NIDDK NIH HHS R01 DK101719
6 · The paper itself

Abstract

purposeLow amplitude rhythmic contractions (LARC) occur in detrusor smooth muscle and may play a role in storage disorders such as overactive bladder and detrusor overactivity. The purpose of this study was to determine whether LARC frequencies identified in vitro from strips of human urinary bladder tissue correlate with in vivo LARC frequencies, visualized as phasic intravesical pressure (p

methodsAfter IRB approval, fresh strips of human urinary bladder were obtained from patients. LARC was recorded with tissue strips at low tension (<2 g) and analyzed by fast Fourier transform (FFT) to identify LARC signal frequencies. Blinded UD tracings were retrospectively reviewed for signs of LARC on the p

resultsDistinct LARC frequencies were identified in 100% of tissue strips (n = 9) obtained with a mean frequency of 1.97 ± 0.47 cycles/min (33 ± 8 mHz). Out of 100 consecutive UD studies reviewed, 35 visually displayed phasic p

conclusionsDuring UD, a subset of patients displayed phasic p

Indexed as

AdultAgedFemaleFourier AnalysisHumansIn Vitro TechniquesMaleMiddle AgedMuscle ContractionMuscle, SmoothPressureUrinary BladderUrinary Bladder, OveractiveUrodynamicsFourier analysisOveractiveSmooth muscleUrinary bladder

Identifiers

PMID28025660
PMCPMC5484740
OpenAlexW2562748408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.