Evidence map›Paper›PMID 28025564›Full record

ArticleBiosensors2016

Versatile Flexible Graphene Multielectrode Arrays.

Dmitry Kireev, Silke Seyock, Mathis Ernst, Vanessa Maybeck, Bernhard Wolfrum, Andreas Offenhäusser

Abstract read
In one paragraph

Article in Biosensors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Graphene Biointerface for Cardiac Arrhythmia Diagnosis and Treatment.Advanced materials (Deerfield Beach, Fla.) · 2023
    Article
  4. Article
  5. Graphene-based cardiac sensors and actuators.Frontiers in bioengineering and biotechnology · 2023
    Review
  6. Article
  7. Frequency-Division Multiplexing with Graphene Active Electrodes for Neurosensor Applications.IEEE transactions on circuits and systems. II, Express briefs : a publication of the IEEE Circuits and Systems Society · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dmitry KireevInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. d.kireev@fz-juelich.de.
Silke SeyockInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. s.seyock@fz-juelich.de.
Mathis ErnstInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. m.ernst@fz-juelich.de.
Vanessa MaybeckInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. v.maybeck@fz-juelich.de.
Bernhard WolfrumInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. bernhard.wolfrum@tum.de.
Andreas OffenhäusserInstitute of Bioelectronics (PGI-8/ICS-8), Forschungszentrum Jülich, 52425 Jülich, Germany. a.offenhaeusser@fz-jueluch.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene is a promising material possessing features relevant to bioelectronics applications. Graphene microelectrodes (GMEAs), which are fabricated in a dense array on a flexible polyimide substrate, were investigated in this work for their performance via electrical impedance spectroscopy. Biocompatibility and suitability of the GMEAs for extracellular recordings were tested by measuring electrical activities from acute heart tissue and cardiac muscle cells. The recordings show encouraging signal-to-noise ratios of 65 ± 15 for heart tissue recordings and 20 ± 10 for HL-1 cells. Considering the low noise and excellent robustness of the devices, the sensor arrays are suitable for diverse and biologically relevant applications.

Indexed as

Biosensing TechniquesGraphiteMicroelectrodesAnimalsCell LineCells, CulturedDielectric SpectroscopyMyocytes, CardiacRatsGraphitecell-graphene interfaceextracellular recordingsGMEAgraphenegraphene electrodes

Identifiers

PMID28025564
PMCPMC5371774

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.