ReviewInternational journal of molecular sciences2016
A Review of Analytical Techniques and Their Application in Disease Diagnosis in Breathomics and Salivaomics Research.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Noninvasive malaria detection beyond blood sampling.Sensors & diagnostics · 2026Review
- Evaluating the VOCORDER device for early disease detection through breath analysis: study protocol for a two-phase clinical study.BMJ open · 2026Article
- Machine learning-enabled diagnosis of viral respiratory infections from exhaled volatile organic compound analysis.BMC pulmonary medicine · 2026Article
- MXene-Based Gas Sensors for NHMicromachines · 2025Review
- Comparisons of Whole Saliva and Cell Free Saliva by DIA-Based Proteome Profiling.Proteomics. Clinical applications · 2025Article
- The Role of Exhaled Breath Condensate in Chronic Inflammatory and Neoplastic Diseases of the Respiratory Tract.International journal of molecular sciences · 2024Review
- Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.Journal of extracellular vesicles · 2024Article
- Two-trace two-dimensional correlation spectra (2T2D-COS) analysis using FTIR spectra to monitor the immune response by COVID-19.Journal of molecular medicine (Berlin, Germany) · 2024Article
- [Development of a widely-targeted metabolomics method based on gas chromatography-mass spectrometry].Se pu = Chinese journal of chromatography · 2023Article
- Unlocking the Diagnostic Potential of Saliva: A Comprehensive Review of Infrared Spectroscopy and Its Applications in Salivary Analysis.Journal of personalized medicine · 2023Review
- Smelling the Disease: Diagnostic Potential of Breath Analysis.Molecular diagnosis & therapy · 2023Review
- Evidence for ethnicity and location as regulators of the newborn blood metabolome: a monozygous twin study.Frontiers in nutrition · 2023Article
- GC-MS-based metabolomics of volatile organic compounds in exhaled breath: applications in health and disease. A review.Frontiers in molecular biosciences · 2023Review
- Exploring a new method for the assessment of metal exposure by analysis of exhaled breath of welders.International archives of occupational and environmental health · 2022Article
- Membrane inlet mass spectrometry method for food intake impact assessment on specific volatile organic compounds in exhaled breath.Analytical and bioanalytical chemistry · 2022Article
- External Validation of a Breath-Based Prediction Model for Malignant Pleural Mesothelioma.Cancers · 2022Article
- Saliva Based Liquid Biopsies in Head and Neck Cancer: How Far Are We From the Clinic?Frontiers in oncology · 2022Review
- Putative Biomarkers for Acute Pulmonary Embolism in Exhaled Breath Condensate.Journal of clinical medicine · 2021Article
- Breath Biomarkers in Diagnostic Applications.Molecules (Basel, Switzerland) · 2021Review
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The application of metabolomics to biological samples has been a key focus in systems biology research, which is aimed at the development of rapid diagnostic methods and the creation of personalized medicine. More recently, there has been a strong focus towards this approach applied to non-invasively acquired samples, such as saliva and exhaled breath. The analysis of these biological samples, in conjunction with other sample types and traditional diagnostic tests, has resulted in faster and more reliable characterization of a range of health disorders and diseases. As the sampling process involved in collecting exhaled breath and saliva is non-intrusive as well as comparatively low-cost and uses a series of widely accepted methods, it provides researchers with easy access to the metabolites secreted by the human body. Owing to its accuracy and rapid nature, metabolomic analysis of saliva and breath (known as salivaomics and breathomics, respectively) is a rapidly growing field and has shown potential to be effective in detecting and diagnosing the early stages of numerous diseases and infections in preclinical studies. This review discusses the various collection and analyses methods currently applied in two of the least used non-invasive sample types in metabolomics, specifically their application in salivaomics and breathomics research. Some of the salient research completed in this field to date is also assessed and discussed in order to provide a basis to advocate their use and possible future scientific directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.