Evidence map›Paper›PMID 28025412›Full record

ArticleExperimental animals2017

Effects of 17β-estradiol on leptin signaling in anterior pituitary of ovariectomized rats.

Chunhua Yin, Lumei Kang, Cong Lai, Jing Zhou, Bin Shi, Lei Zhang, Hongping Chen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental animals, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. 3 Biotech · 2023
    Article
  2. Prophylactic effect ofJournal of traditional and complementary medicine · 2022
    Article
  3. Article
  4. Review
  5. Maternal exposure to bisphenol A during pregnancy interferes testis development of F1 male mice.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chunhua YinDepartment of Gynecology and Obstetric, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Lumei KangDepartment of Animal Science, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Cong LaiDepartment of Histology and Embryology, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Jing ZhouDepartment of Histology and Embryology, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Bin ShiDepartment of Histology and Embryology, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Lei ZhangDepartment of Histology and Embryology, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Hongping ChenDepartment of Histology and Embryology, Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptin is secreted predominantly by adipocytes and exerts its role mainly by interaction with the long form of leptin receptor (LEPR_V2). It has been identified that LEPR_V2 is widely distributed in various tissues, including the anterior pituitary. Cross-talk between leptin and estrogens has been indentified. Estrogen is known to modulate the tissue-specific expression of LEPR_V2 and leptin in ovariectomized (OVX) rats, a model of postmenopausal condition. Our previous data showed that 17β-estradiol (E

Indexed as

OvariectomyAdipocytesAnimalsDose-Response Relationship, DrugEstradiolEstrogensFemaleLeptinMenopauseModels, AnimalPituitary Gland, AnteriorRats, Sprague-DawleyReceptor Cross-TalkReceptors, LeptinRNA, MessengerSignal TransductionEstradiolEstrogensLeptinReceptors, LeptinRNA, MessengerSocs3 protein, ratStat3 protein, ratSTAT3 Transcription FactorSuppressor of Cytokine Signaling 3 Protein17β-estradiolanterior pituitaryleptinleptin receptorovariectomized rat

Identifiers

PMID28025412
PMCPMC5411302
OpenAlexW2563010569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.