Trial reportPain medicine (Malden, Mass.)2016
Development and Preliminary Evaluation of an Integrated Cognitive-Behavior Treatment for Chronic Pain and Substance Use Disorder in Patients with the Hepatitis C Virus.
Trial report in Pain medicine (Malden, Mass.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain.Drug and alcohol dependence · 2019Trial
- Use of Cognitive-Behavioral Therapy in a Nation-Wide Veterans Health Administration Sample: The Role of Clinic, Therapist, and Patient Factors.Health services research · 2025Article
- Article
- Integrating chronic pain management into care for patients with opioid use disorder.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Article
- Recent advances in the treatment of chronic pain and substance use disorders.Current opinion in psychology · 2025Review
- Translating an Intervention to Address Chronic Pain among Home Care Workers: The COMPASS-NP Pilot.Journal of occupational and environmental medicine · 2024Article
- Alcohol Use Disorder and Chronic Pain: An Overlooked Epidemic.The American journal of psychiatry · 2024Review
- A Research Agenda for Advancing Strategies to Improve Opioid Safety: Findings from a VHA State of the Art Conference.Journal of general internal medicine · 2020Article
- Chronic non-cancer pain among adults with substance use disorders: Prevalence, characteristics, and association with opioid overdose and healthcare utilization.Drug and alcohol dependence · 2020Article
- Alcohol and Pain: A Translational Review of Preclinical and Clinical Findings to Inform Future Treatment Strategies.Alcoholism, clinical and experimental research · 2020Review
- Childhood Trauma, Emotion Regulation, and Pain in Individuals With Alcohol Use Disorder.Frontiers in psychiatry · 2020Article
- Pain Diagnosis, Pain Coping, and Function in Individuals with Chronic Musculoskeletal Pain.Journal of pain research · 2020Article
- Clinician Response to Aberrant Urine Drug Test Results of Patients Prescribed Opioid Therapy for Chronic Pain.The Clinical journal of pain · 2019Article
- Substance Use Disorder Treatment Following Clinician-Initiated Discontinuation of Long-Term Opioid Therapy Resulting from an Aberrant Urine Drug Test.Journal of general internal medicine · 2017Article
- Patterns and correlates of medical cannabis use for pain among patients prescribed long-term opioid therapy.General hospital psychiatryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveIndividuals with the hepatitis C virus (HCV) have high rates of both chronic pain and substance use disorder (SUD). Despite high comorbidity, there are limited data available on effective methods of treatment for co-occurring chronic pain and SUD. In this study, we sought to develop and conduct preliminary testing of an integrated cognitive-behavior therapy (CBT) for chronic pain and SUD in patients with HCV.
designDescriptive, including pretreatment, posttreatment, and follow-up testing. SETTING AND PATIENTS: Outpatient clinic as part of one VA Medical Center.
participantsVeterans with chronic pain, SUD, and HCV.
interventionEight-session integrated group CBT for chronic pain and SUD in patients with HCV.
methodsParticipants completed standardized measures of pain, function, depression severity, and alcohol and substance use at baseline, post-treatment, and 3-month follow-up.
resultsGeneralized estimating equations identified improvements in pain interference, reducing cravings for alcohol and other substances, and decreasing past-month alcohol and substance use. The proportion of participants who met diagnostic criteria for current SUD demonstrated a four-fold decrease over the course of the study from 24% at baseline to 15% at post-treatment and 6% at 3-month follow-up. On response to a global impression of change, 94% of participants noted improvement from baseline.
conclusionsResults from this pilot study suggest that a customized CBT for patients with both chronic pain and SUD (CBT-cp.sud) may be beneficial in improving important pain and addiction-related outcomes in patients with HCV. Larger scale investigations of this intervention appear warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.