ArticlePsychiatry research. Neuroimaging2017
Switching between internally and externally focused attention in obsessive-compulsive disorder: Abnormal visual cortex activation and connectivity.
Article in Psychiatry research. Neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exploring functional connectivity in large-scale brain networks in obsessive-compulsive disorder: a systematic review of EEG and fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- Functional connectivity alterations between default mode network and occipital cortex in patients with obsessive-compulsive disorder (OCD).NeuroImage. Clinical · 2022Pooled it
- Impaired disengagement from worry: Dissociating the impacts of valence and internally-directed attention.Behaviour research and therapy · 2023Trial
- Altered seed-to-whole-brain functional connectivity of goal-directed/habitual systems in obsessive-compulsive disorder: associated genes and preliminary classification potential.European archives of psychiatry and clinical neuroscience · 2026Article
- Theta-Alpha Dysregulation reveals impaired endogenous cognitive control in adolescent Obsessive-Compulsive disorder.NeuroImage. Clinical · 2026Article
- Brain Network Abnormalities in Obsessive-Compulsive Disorder: Insights from Edge Functional Connectivity Analysis.Behavioral sciences (Basel, Switzerland) · 2025Article
- Abnormal static and dynamic functional connectivity of striatal subregions in patients with obsessive-compulsive disorder.Frontiers in psychiatry · 2025Article
- Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia.Neuroscience of consciousness · 2025Article
- Age of onset of obsessive-compulsive disorder differentially affects white matter microstructure.Molecular psychiatry · 2024Article
- Cognitive inflexibility is linked to abnormal frontoparietal-related activation and connectivity in obsessive-compulsive disorder.Human brain mapping · 2023Article
- Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls.Nature communications · 2023Article
- Abnormal resting-state functional connectivity of the insula in medication-free patients with obsessive-compulsive disorder.BMC psychiatry · 2022Article
- Functional Connectivity within the Frontal-Striatal Network Differentiates Checkers from Washers of Obsessive-Compulsive Disorder.Brain sciences · 2022Article
- Neural basis of associative learning in Trichotillomania and skin-picking disorder.Behavioural brain research · 2022Article
- Characterizing multiscale modular structures in medication-free obsessive-compulsive disorder patients with no comorbidity.Human brain mapping · 2022Article
- Imbalance between default mode and sensorimotor connectivity is associated with perseverative thinking in obsessive-compulsive disorder.Translational psychiatry · 2022Article
- Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort.Psychiatry research · 2020Article
- Disrupted brain network dynamics and cognitive functions in methamphetamine use disorder: insights from EEG microstates.BMC psychiatry · 2020Article
- Signatures of alcohol use in the structure and neurochemistry of insular cortex: a correlational study.Psychopharmacology · 2019Article
- Investigating the predictive value of different resting-state functional MRI parameters in obsessive-compulsive disorder.Translational psychiatry · 2019Article
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Abstract
Obsessive-compulsive disorder (OCD) is characterized by excessive absorption with internally-generated distressing thoughts and urges, with difficulty incorporating external information running counter to their fears and concerns. In the present study, we experimentally probed this core feature of OCD through the use of a novel attention switching task that investigates transitions between internally focused (IF) and externally focused (EF) attentional states. Eighteen OCD patients and 18 controls imagined positive and negative personal event scenarios (IF state) or performed a color-word Stroop task (EF state). The IF/EF states were followed by a target detection (TD) task requiring responses to external stimuli. Compared to controls, OCD patients made significantly more errors and showed reduced activation of superior and inferior occipital cortex, thalamus, and putamen during TD following negative IF, with the inferior occipital hypoactivation being significantly greater for TD following negative IF compared to TD following the other conditions. Patients showed stronger functional connectivity between the inferior occipital region and dorsomedial prefrontal cortex. These findings point to an OCD-related impairment in the visual processing of external stimuli specifically when they follow a period of negative internal focus, and suggest that future treatments may wish to target the transition between attentional states.
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