Evidence map›Paper›PMID 28024420›Full record

Observational studyIntegrative cancer therapies2018

Assessing the Correlation Between Physical Activity and Quality of Life in Advanced Lung Cancer.

Brett C Bade, Mary C Brooks, Sloan B Nietert, Ansley Ulmer, D David Thomas, Paul J Nietert, JoAnn B Scott, Gerard A Silvestri

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Integrative cancer therapies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Association between physical activity and patient-reported outcome measures in patients with lung cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  4. Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
    Pooled it
  5. Smartphone measurements of physical activity and fitness are associated with early trial discontinuation of patients in (hemato)oncology phase I/II clinical trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  6. Trial
  7. Home-based rehabilitation in inoperable non-small cell lung cancer-the patient experience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Trial
  8. Trial
  9. Review
  10. Survivorship Challenges and Supportive Care in Lung Cancer.Seminars in respiratory and critical care medicine · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Brett C Bade1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
Mary C Brooks1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
Sloan B Nietert2 Academic Magnet High School, North Charleston, SC, USA.
Ansley Ulmer2 Academic Magnet High School, North Charleston, SC, USA.
D David Thomas1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
Paul J Nietert1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
JoAnn B Scott1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
Gerard A Silvestri1 Medical University of South Carolina (MUSC), Charleston, SC, USA.
Medical University of South Carolina · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
NCATS NIH HHS UL1 TR000062NCATS NIH HHS UL1 TR001450NCATS NIH HHS UL1 TR001863NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

BACKGROUND AND

objectiveIncreasing physical activity (PA) is safe and beneficial in lung cancer (LC) patients. Advanced-stage LC patients are under-studied and have worse symptoms and quality of life (QoL). We evaluated the feasibility of monitoring step count in advanced LC as well as potential correlations between PA and QoL.

methodsThis is a prospective, observational study of 39 consecutive patients with advanced-stage LC. Daily step count over 1 week (via Fitbit Zip), QoL, dyspnea, and depression scores were collected. Spearman rank testing was used to assess correlations. Correlation coefficients (ρ) >0.3 or <-0.3 (more and less correlated, respectively) were considered potentially clinically significant.

resultsMost (83%) of the patients were interested in participating, and 67% of those enrolled were adherent with the device. Of those using the device (n = 30), the average daily step count was 4877 (range = 504-12 118) steps/d. Higher average daily step count correlated with higher QoL (ρ = 0.46), physical (ρ = 0.61), role (ρ = 0.48), and emotional functioning (ρ = 0.40) scores as well as lower depression (ρ = -0.40), dyspnea (ρ = -0.54), and pain (ρ = -0.37) scores.

conclusionRemote PA monitoring (Fitbit Zip) is feasible in advanced-stage LC patients. Interest in participating in this PA study was high with comparable adherence to other PA studies. In those utilizing the device, higher step count correlates with higher QoL as well as lower dyspnea, pain, and depression scores. PA monitoring with wearable devices in advanced-stage LC deserves further study.

Indexed as

ExerciseAccelerometryAgedAged, 80 and overExercise TestFeasibility StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedMonitoring, AmbulatoryPrognosisProspective StudiesQuality of LifeRemote Sensing Technologyexercisenon–small-cell lung cancerphysical activityquality of lifesmall-cell lung cancer

Identifiers

PMID28024420
PMCPMC5647199
OpenAlexW2564914915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.