ArticleJournal of veterinary internal medicine2017
Proteinuria in Apparently Healthy Elderly Dogs: Persistency and Comparison Between Free Catch and Cystocentesis Urine.
Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Evaluation of Urinary Tubular Biomarkers in Dogs with Myxomatous Mitral Valve Disease Across ACVIM Stages.Veterinary sciences · 2026Article
- Second-Degree Atrioventricular Block With Steroid-Induced Diabetes Mellitus in a Miniature Poodle.Veterinary medicine and science · 2025Article
- Use of urinalysis during baseline diagnostics in dogs and cats: an open survey.The Journal of small animal practice · 2023Article
- The Relevance of Screening for Vector-Borne Diseases in Dogs with Proteinuria Living in an Endemic Region: A Retrospective Study.Veterinary sciences · 2022Article
- Alterations of Serum Biochemical and Urinary Parameters in a Canine Population before and after Intravenous Contrast Administration.Veterinary sciences · 2021Article
- Prevalence of Proteinuria in Owned Dogs from Italy: A Multicentric Study.Veterinary medicine international · 2019Article
- Relationships among urinary protein-to-creatinine ratio, urine specific gravity, and bacteriuria in canine urine samples.Journal of veterinary internal medicine · 2019Article
- Variability of serum concentrations of cystatin C and urinary retinol-binding protein, neutrophil gelatinase-associated lipocalin, immunoglobulin G, and C-reactive protein in dogs.Journal of veterinary internal medicine · 2018Article
- Clinical Consequences of Hypertriglyceridemia-Associated Proteinuria in Miniature Schnauzers.Journal of veterinary internal medicine · 2017Article
- Comparison of cystocentesis versus home sampling to determine urinary protein: Creatinine ratio and urine specific gravity in cats.Journal of veterinary internal medicineArticle
- Longitudinal Study of Renal Health Screening in Apparently Healthy Aging Dogs.Journal of veterinary internal medicineArticle
- Is proteinuria a rare condition in apparently healthy and sick cats? A feline practice experience (2007-2018).Open veterinary journalArticle
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUp to 25% of elderly humans have proteinuria, often associated with underlying lesions. Data concerning the presence of proteinuria in elderly dogs is scarce.
objectivesTo describe the presence and persistence of proteinuria and to compare urinary protein : creatinine ratio (UPC) between free catch and cystocentesis urine samples in apparently healthy elderly dogs. ANIMALS: Hundred apparently healthy elderly dogs.
methodsProspective study. Owners of 100 elderly dogs were asked to collect 2 free catch urine samples. Dogs were considered healthy based on owner's perception and an age chart, based on ideal bodyweight, was used to define dogs as senior or geriatric. UPC of urine collected by free catch and cystocentesis were compared. Overt proteinuria and borderline proteinuria were defined as UPC >0.5 and between 0.2 and 0.5, respectively, if examination of sediment did not explain proteinuria. Proteinuria was considered persistent if present at both sampling times.
resultsAt baseline, 71 owners succeeded in collecting urine. Eleven percent of dogs had overt proteinuria, 14% were borderline proteinuric, and 75% nonproteinuric. Thirty-seven repeated urine samples, with a median time interval of 31 days (range 10-90), were available. Nineteen percent of dogs had a persistently increased UPC (>0.2), with persistent overt proteinuria present in 8%. A strong correlation (ρ = 0.88) was found between UPC of urine collected by free catch and cystocentesis. CONCLUSIONS AND CLINICAL IMPORTANCE: As 19% of study dogs had persistent proteinuria, our findings emphasize that measurement of proteinuria should be part of geriatric health screening. For UPC in dogs, free catch urine provides a good alternative to cystocentesis.
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