ArticleCMAJ open
Hospital admissions for lower respiratory tract infections among infants in the Canadian Arctic: a cohort study.
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Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18citing papers in PubMed, 1 pooled it
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Practical Guidance for Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections.Clinical microbiology reviews · 2019Guideline
- Acute Respiratory Tract Infections and Severe Disease Among Hospitalized Children.JAMA network open · 2026Article
- Healthcare costs and resource utilization for acute respiratory syncytial virus pediatric hospitalizations in Canada: a population-based study.Lancet regional health. Americas · 2025Article
- Hospital admissions for acute respiratory tract infections among infants from Nunavut and the burden of respiratory syncytial virus: a 10-year retrospective cohort study.Lancet regional health. Americas · 2025Article
- Cost-effectiveness of nirsevimab and maternal RSVpreF for preventing respiratory syncytial virus disease in infants across Canada.BMC medicine · 2025Article
- A Scoping Review of the Current Knowledge of the Social Determinants of Health and Infectious Diseases (Specifically COVID-19, Tuberculosis, and H1N1 Influenza) in Canadian Arctic Indigenous Communities.International journal of environmental research and public health · 2024Article
- Article
- Cost-utility analysis of palivizumab for preventing respiratory syncytial virus in preterm neonates and infants in Colombia.BMC infectious diseases · 2024Article
- Estimating the Incidence of First RSV Hospitalization in Children Born in Ontario, Canada.Journal of the Pediatric Infectious Diseases Society · 2023Article
- Housing conditions and respiratory morbidity in Indigenous children in remote communities in Northwestern Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Urgent air transfers for acute respiratory infections among children from Northern Canada, 2005-2014.PloS one · 2022Article
- Burden of illness in infants and young children hospitalized for respiratory syncytial virus: A rapid review.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Article
- Association of theFrontiers in pediatrics · 2021Article
- Effectiveness of palivizumab immunoprophylaxis to prevent respiratory syncytial virus hospitalizations in healthy full-term <6-month-old infants from the circumpolar region of Nunavik, Quebec, Canada.Preventive medicine reports · 2020Article
- Feasibility and ethical issues: experiences and concerns of healthcare workers regarding a new RSV prophylaxis programme in Nunavik, Quebec.International journal of circumpolar health · 2020Article
- Reducing the burden of lower respiratory tract infections in infants in the Canadian Arctic.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Article
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Authors and funding
16 authors at 6 institutions in 2 countries.
Anna BanerjiLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Val PanzovLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Michael YoungLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Joan RobinsonLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Bonita LeeLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Theo MoraesLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Muhammad MamdaniLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
B Louise GilesLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Depeng JiangLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Danny BissonLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Marguerite DennisLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Johanne MorelLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Judith HallLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Charles HuiLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Bosco PaesLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
James B MahonyLi Ka Shing Knowledge Institute (Banerji); Applied Health Research Centre (Panzov, Mamdani, Hall), St. Michael's Hospital, Toronto, Ont.; Dalla Lana School of Public Health (Banerji), University of Toronto, Toronto, Ont.; Department of Pediatrics (Young), Dalhousie University; Department of Emergency Medicine (Young), IWK Health Centre, Halifax, NS; Infectious Diseases (Robinson), Stollery Children's Hospital; Department of Pediatrics (Lee), University of Alberta, Edmonton Clinic Health Academy, Edmonton, Alta.; Division of Respiratory Medicine (Moraes), Department of Pediatrics, Hospital for Sick Children, Toronto, Ont.; Respirology (Giles), Winnipeg Children's Hospital; Department of Community Health Sciences (Jiang); J.A. Hildes Northern Medical Unit (Bisson), University of Manitoba, Winnipeg, Man.; Pediatrics (Dennis), Sunnybrook Health Sciences Centre, Toronto, Ont.; Pediatrics (Morel), Montreal Children's Hospital, Montréal, Que.; Department of Pediatrics (Hui), Children's Hospital of Eastern Ontario, Ottawa, Ont.; Department of Pediatrics (Paes), McMaster Children's Hospital; Department of Virology Laboratory (Mahony), St. Joseph's Hospital, Hamilton, Ont.
Li Ka Shing Foundation · CNSt. Michael's Hospital · CAIzaak Walton Killam Health Centre · CAStollery Children's Hospital · CAChildren's Hospital of Winnipeg · CADalhousie University · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is unknown whether this burden of disease of lower respiratory tract infections is comparable across the Canadian Arctic. The objectives of this surveillance study were to compare the rates of hospital admission for lower respiratory tract infection and the severity of infection across Arctic Canada, and to describe the responsible viruses.
methodsWe performed a prospective multicentre surveillance study of infants less than 1 year of age admitted in 2009 with lower respiratory tract infection to all hospitals (5 regional, 4 tertiary) in the Northwest Territories, Nunavut and Nunavik to assess for regional differences. Nasopharyngeal aspirates were processed by means of a polymerase chain reaction respiratory viral panel, testing for 20 respiratory viruses and influenza A (H1N1). The role of coinfection was assessed by means of regression analysis for length of stay (short: < 7 d; long: > 14 d). Outcomes compared included rates of lower respiratory tract infection, respiratory syncytial virus infection, transfer to tertiary hospital and severe lower respiratory tract infection (respiratory failure, intubation and mechanical ventilation, and/or cardiopulmonary resuscitation).
resultsThere were 348 admissions for lower respiratory tract infection in the population of interest in 2009. Rates of admission per 1000 live births varied significantly, from 39 in the Northwest Territories to 456 in Nunavik (
interpretationNunavut and Nunavik have very elevated rates of lower respiratory tract infection, with severe outcomes. Respiratory syncytial virus was the most common virus identified, and coinfection was associated with longer length of stay. Targeted public health interventions are required to reduce the burden of disease for infants residing in these Arctic regions.
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